THE IMMUNOLOGICAL INDICATORS OF PERSONALIZED PRESCRIPTIONS FOR ALLOIMMUNIZATION IN THE THERAPY OF IDIOPATHIC RECCURENT MISCARRIAGE
- Authors: Krechetova L.V.1, Tetruashvili N.K.1, Vtorushina V.V.1, Nikolaeva M.A.1, Vanko L.V.1
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Affiliations:
- National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V. I. Kulakov of Ministry of Healthcare of Russian Federation
- Issue: Vol 22, No 2-1 (2019)
- Pages: 341-343
- Section: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/119928
- DOI: https://doi.org/10.31857/S102872210006621-8
- ID: 119928
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Abstract
This article represents the results of the lymphocyte’s subpopulation analysis of women with idiopathic reccurent pregnancy loss (RPL) after lymphocyte immune therapy (LIT). It reveals the dependence of successful childbearing in women with RPL on the cellular immune system, validates the term of alloimmune genesis of recurrent miscarriage is eligible. It identifi es the indicators for personalized prescriptions for LIT and indicators of favorable prognosis of successful pregnancy in woman with RPL after LIT.
About the authors
L. V. Krechetova
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V. I. Kulakov of Ministry of Healthcare of Russian Federation
Author for correspondence.
Email: k_l_v_@mail.ru
Ph.D. in medical sciences, Head of Laboratory of Clinical Immunology,
Moscow
Russian FederationN. K. Tetruashvili
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V. I. Kulakov of Ministry of Healthcare of Russian Federation
Doctor of Medicine, Head of the Department of Pregnancy Loss Prevention and Therapy,
Moscow
Russian FederationV. V. Vtorushina
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V. I. Kulakov of Ministry of Healthcare of Russian Federation
Ph.D. in medical sciences, doctor of laboratory diagnostics in Laboratory of Clinical Immunology,
Moscow
Russian FederationM. A. Nikolaeva
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V. I. Kulakov of Ministry of Healthcare of Russian Federation
Doctor of Science, Leading researcher, Laboratory of Clinical Immunology,
Moscow
Russian FederationL. V. Vanko
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V. I. Kulakov of Ministry of Healthcare of Russian Federation
doctor of medicine, professor, leading research worker of clinical immunology laboratory,
Moscow
Russian FederationReferences
- Кречетова Л. В., Хачатрян Н. А., Тетруашвили Н. К., Вторушина В. В., Степанова Е. О., Николаева М. А., Сухих Г. Т. Особенности фенотипа лимфоцитов периферической крови женщин с привычным выкидышем //Акушерство и гинекология. – 2014. – № 10. – С. 27–33.
- Л. В. Кречетова, Н. К. Тетруашвили, В. В. Вторушина, М. А. Николаева, Н. А. Хачатрян, А. А. Агаджанова, Л. В. Ванько, Т. Ю. Иванец, Г. Т. Сухих. Особенности фенотипа лимфоцитов периферической крови женщин с идиопатическим привычным выкидышем в зависимости от исхода беременности на фоне иммуноцитотерапии // Акушерство и гинекология. – 2017. – № 7. – С. 52–60.
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