INFLUENCE OF MP-3 ON PRODUCTION OF ACTIVE OXYGEN FORMS, IL-1 β AND TNF-α BY PERITONEAL MACROPHAGES IN PENETRATING EYE INJURY

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Abstract

Thus, myelopeptide MP-3 has a modulating effect on the function of peritoneal macrophages, eliminating enhancement of IL-1β under penetrating eye injury.

About the authors

T. V. Gavrilova

Institute of Ecology and Genetics of Microorganisms, Ural Branch, Russian Academy of Sciences; Academician Ye. A. Vagner Perm State Medical University

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

L. S. Zhuravleva

Institute of Ecology and Genetics of Microorganisms, Ural Branch, Russian Academy of Sciences

Email: noemail@neicon.ru
Russian Federation

M. V. Chereshneva

Institute of Immunology and Physiology, Ural Branch, Russian Academy of Sciences; Academician Ye. A. Vagner Perm State Medical University

Email: noemail@neicon.ru
Russian Federation

S. V. Gein

Institute of Ecology and Genetics of Microorganisms, Ural Branch, Russian Academy of Sciences; Perm State University

Email: noemail@neicon.ru
Russian Federation

E. A. Kirilina

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences

Email: noemail@neicon.ru
Russian Federation

V. A. Chereshnev

Institute of Immunology and Physiology, Ural Branch, Russian Academy of Sciences; Academician Ye. A. Vagner Perm State Medical University

Email: noemail@neicon.ru
Russian Federation

References

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  2. Черешнева М. В., Шилов Ю. И., Гаврилова Т. В. др. Иммунокоррекция травматических и стрессорных нарушений функций иммунной системы при проникающем ранении глаза. Вестник офтальмологии, 2006, № 1, 42-46.
  3. Гундорова Р. А., Малаев А. А., Южаков А. М. Травмы глаза. М.: Медицина, 1986, 364.
  4. Гейн С. В., Гаврилова Т. В., Журавлёва Л. С. и др. Влияние МП-3 на динамику респираторного взрыва и продукцию IL-1P и TNF-α перитонеальными макрофагами мыши при стрессе in vivo. Доклады академии наук, 2014, 455, 2, 232-234.

Copyright (c) 2017 Gavrilova T.V., Zhuravleva L.S., Chereshneva M.V., Gein S.V., Kirilina E.A., Chereshnev V.A.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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