RECEPTOR AND PHAGOCYTIC ACTIVITY OF NEUTROPHILS IN CHRONIC DISEASES OF THE UPPER GASTROINTESTINAL TRACT IN CHILDREN, ASSOCIATED WITH HELICOBACTER PYLORI, AND FUNGI OF THE GENUS CANDIDA
- Authors: Agafonova E.V.1, Velinsky T.A.1
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Affiliations:
- Kazan state medical University FBUN KNIIM Central research Institute of Rospotrebnadzor
- Issue: Vol 20, No 2 (2017)
- Pages: 241-243
- Section: Articles
- URL: https://journals.rcsi.science/1028-7221/article/view/119767
- ID: 119767
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Abstract
In children with chronic diseases of the upper gastrointestinal tract associated with Helicobacter pylori, and Helicobacter pylori association with fungi of the genus Candida, study of the receptor apparatus (adhesion, to the components of complement-CR 3, Fc fragment of Ig G and activation markers) and phagocytic activity of neutrophils. The identified differentiated characteristics of the phagocytic activity and immunophenotype in Helicobacter pylori infection and association with fungi of the genus Candida. Mannoproteins circulating antigen of Candida albicans affects the immunophenotype of neutrophils, inducing the expression of proapoptotic and reducing the expression of adhesion receptors and cytolysis.
About the authors
E. V. Agafonova
Kazan state medical University FBUN KNIIM Central research Institute of Rospotrebnadzor
Author for correspondence.
Russian Federation
T. A. Velinsky
Kazan state medical University FBUN KNIIM Central research Institute of RospotrebnadzorRussian Federation
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