PECULIARITIES OF IMMUNE REGULATION IN CHILDREN UNDER INDUSTRIAL EXPOSURE TO METALS

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Abstract

Changes of immune parameters in children under conditions of industrial metals contamination were associated with a decrease in phagocytic activity, inhibition of CD4 and CD95 expression and an augmentation in the number of CD25+ and CD127- lymphocytes, an increase in IgE content of total and specific IgG to aluminum, activation of synthesis of non-specific mediators of leukotrienes C4/D4/E4.

About the authors

O. V. Dolgikh

FBUN "Federal scientific center of medico-preventive technologies of risk management to health of the population

Author for correspondence.
Russian Federation

K. G. Starkova

FBUN "Federal scientific center of medico-preventive technologies of risk management to health of the population

Russian Federation

E. A. Otavina

FBUN "Federal scientific center of medico-preventive technologies of risk management to health of the population

Russian Federation

O. A. Kazakova

FBUN "Federal scientific center of medico-preventive technologies of risk management to health of the population

Russian Federation

M. A. Guselnikov

FBUN "Federal scientific center of medico-preventive technologies of risk management to health of the population

Russian Federation

I. G. Zhdanova

FBUN "Federal scientific center of medico-preventive technologies of risk management to health of the population

Russian Federation

References

  1. Cмагулов Н. К. Ажиметова Г. Н. Международный журнал экспериментального образования. 2013, 11, 57-60.
  2. Duramad P., Holland N. T. Int. J. Environ. Res. Public Health. 2011, 8 (5), 1388-1401.
  3. Долгих О. В., Кривцов А. В., Бубнова О. А., Отавина Е. А., Безрученко Н. В. и др. Гигиена и санитария. 2017, 96(1), 26-29.
  4. Lehmann I., Sack U., Lehmann J. Met. Ions Life Sci. 2011,8,157-185.

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Copyright (c) 2017 Dolgikh O.V., Starkova K.G., Otavina E.A., Kazakova O.A., Guselnikov M.A., Zhdanova I.G.

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