THE STATE OF LOCAL IMMUNITY IN ADOLESCENTS WITH CHRONIC GINGIVITIS
- Authors: Dzech O.Y.1, Lazarev A.I.2
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Affiliations:
- Belgorod State University
- Kursk State Medical University
- Issue: Vol 22, No 2-2 (2019)
- Pages: 757-759
- Section: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/119501
- DOI: https://doi.org/10.31857/S102872210006711-7
- ID: 119501
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Abstract
Adolescents with chronic catarrhal gingivitis aged from 14 to 17 years without general somatic pathology affecting the etiopathogenesis of inflammatory periodontal diseases were observed. Of the total number of patients examined, 19 were at the stage of ortho-dontic treatment. The control group consisted of 40 clinically healthy patients. The state of the local immune status of the oral cavity was assessed by the functional activity of phagocytes, the content of mixed saliva IgA, IgM, IgG, sIgA, IL-4, IL-8 by solid-phase enzyme immunoassay. In adolescents with chronic gingivitis, there are clearly pronounced shifts in local immunity, which are represented by an increase in the of IgG, sIgA, IL-4, IL-8, the functional reserve of neutrophils, index stimulation of neutrophils compared to the control group, as well as a decrease in the level of IgM and the concentration of oxygen-dependent enzymes in the cytoplasm of phagocytes in the nbt-spontaneous test.
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About the authors
O. Yu. Dzech
Belgorod State University
Author for correspondence.
Email: denitatyana@yandex.ru
Postgraduate Student, Department of Pharmacology,
Belgorod
sh.77@mail.ru
Russian FederationA. I. Lazarev
Kursk State Medical University
Email: fake@neicon.ru
M.D., Department of Otorhinolaryngology,
Kursk
Russian FederationReferences
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