ABILITY OF CONDITIONALLY-PATHOGENIC MICROORGANISM TO INACTIVATE ANTI-MICROBIAL PROTEIN BY LYSOZYM UNDER THE INFLUENCE OF METABOLITES ASSOCIATION OF BIFIDOBACTERIA
- Authors: Bekpergenova A.V.1, Perunova N.B.1, Andryushenko S.V.1, Zdvizhkova I.A.1, Mironova A.R.2
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Affiliations:
- FGBUN Institute for Cellular and Intracellular Symbiosis
- GBUZ Orenburg Regional Clinical Infectious Diseases Hospital, Orenburg
- Issue: Vol 22, No 2-1 (2019)
- Pages: 156-158
- Section: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/119424
- DOI: https://doi.org/10.31857/S102872210006433-1
- ID: 119424
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Abstract
Materials on the eff ect of the supernatants of the associations of bifi dobacteria on the antilysozyme activity of microorganisms are presented. An increase in the antilysozyme activity was detected in the lactosopositive non-hemolytic strains of E. coli isolated during human intestinal eubiosis, and, conversely, a decrease in hemolytic E. coli, S. aureus and C. albicans isolated in dysbiosis. The available materials contribute to the study of the mechanisms of formation of microsymbiosis in the associative symbiosis of humans and contribute to the identifi cation of strains of bifi dobacteria, suitable as pro- and metabiotics.
About the authors
A. V. Bekpergenova
FGBUN Institute for Cellular and Intracellular Symbiosis
Author for correspondence.
Email: nsavasteeva@gmail.com
Researcher, Laboratory of Biomonitoring and Molecular Genetic Research,
Orenburg
Russian FederationN. B. Perunova
FGBUN Institute for Cellular and Intracellular Symbiosis
PhD, Professor RAS, Associate Professor Laboratory of Biomonitoring and Molecular Genetic Research,
Orenburg
Russian FederationS. V. Andryushenko
FGBUN Institute for Cellular and Intracellular Symbiosis
PhD, Associate Professor Laboratory of Biomonitoring and Molecular Genetic Research,
Orenburg
Russian FederationI. A. Zdvizhkova
FGBUN Institute for Cellular and Intracellular Symbiosis
Researcher, Laboratory of Biomonitoring and Molecular Genetic Research,
Orenburg
Russian FederationA. R. Mironova
GBUZ Orenburg Regional Clinical Infectious Diseases Hospital, Orenburg
Head of Bacteriological Laboratory,
Orenburg
Russian FederationReferences
- Бухарин О. В. Персистенция патогенных бактерий. М.: Медицина, 1999, 322.
- Шендеров Б. А. Медицинская микробная экология и функциональное питание. М.: ГАРАНТЪ. 1998, 1, 288.
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