MICROVESICLES IN FOLLICULAR FLUID WITH WOMEN IN IVF PROGRAM

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Abstract

Microvesicles has a signifi cant potential as a new diagnostic and prognostic biomarker including reproductive pathologies. In this paper shown that an elevated level of microvesicles in women’s follicular fluid is associated with the age, the duration of infertility and clinical pregnancy.

About the authors

E. A. Andreeva

Institute of Fundamental and Clinical Immunology

postgraduate student of the laboratory cell immunotherapy;

Novosibirsk

Russian Federation

N. A. Khonina

Institute of Fundamental and Clinical Immunology;
Novosibirsk State University

Author for correspondence.
Email: nkhonina@mail.ru

MD., Leading Researcher of the laboratory cell immunotherapy,

Novosibirsk

Russian Federation

N. M. Pasman

Novosibirsk State University

PhD, MD, Professor (Medicine), Head of Department of Obstetrics and Gynecology,

Novosibirsk

Russian Federation

References

  1. Yuana Y., Sturk A., Nieuwland R. Extracellular vesicles in physiological and pathological conditions. Blood Reviews. 2013, 27, 31–39.
  2. Lawson C., Vicencio J., Yellon D. M., Davidson S. M. Microvesicles and exosomes: new players in metabolic and cardiovascular disease. J Endocrinol. 2016, 228, 2, R57–71.
  3. Machtinger R., Laurent L. C., Baccarelli A. Extracellular vesicles: roles in gamete maturation, fertilization and embryo implantation. Hum Reprod Update. 2016; 22(2), 182–193.
  4. Tannetta D., Dragovic R., Alyahyaei Z., Southcombe J. Cellular and Extracellular vesicles and reproduction– promotion of successful pregnancy. Molecular Immunology. 2014, 11, 548–563.

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Copyright (c) 2019 Andreeva E.A., Khonina N.A., Pasman N.M.

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