INFLUENCE OF OZONOTHERAPY ON IMMUNE STATUS AT ISOLATED FRACTURES OF THE FEMORAL BONE

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Abstract

The study of the dynamics of the immune system parameters in men of working age with an isolated fracture of the femur in the early post-traumatic period showed the formation of an immunosuppressive background, due to an increase in the circulation of T-regulatory cells. The use of ozone therapy in the form of small autohemotherapy reduces the manifestations of immunosuppression by reducing the number of T-regulatory cells in the bloodstream against the background of an increase in the number of natural killer cells, which will make it possible to reduce the number of infectious complications.

About the authors

K. S. Abramov

”South Ural State Medical University” of the Ministry of Health of Russia

Author for correspondence.
Email: prof.osikov@yandex.ru

Senior Laboratory Assistant, Department of Pathological Physiology,

Chelyabinsk

Russian Federation

E. V. Davydova

”South Ural State Medical University” of the Ministry of Health of Russia

MD, associate professor, professor of the Department of Pathological Physiology, 

Chelyabinsk

Russian Federation

M. V. Osikov

”South Ural State Medical University” of the Ministry of Health of Russia

MD, Professor, Head. Department of Pathological Physiology,

Chelyabinsk

Russian Federation

S. A. Kochengina

Chelyabinsk Regional Children’s Clinical Hospital

Ph.D., doctor of clinical and laboratory diagnostics,

Chelyabinsk

Russian Federation

References

  1. Agarwal-Harding K.J., Meara J. G., Greenberg S. L., Hagander L. E., Zurakowski D., Dyer G. S. Estimating the global incidence of femoral fracture from road traffic collisions: a literature review. J Bone Joint Surg Am. 2015, 18, 97(6): e31. doi: 10.2106/JBJS.N.00314. (Типовая, англоязычная)
  2. Re L., Martínez-Sánchez G., Bordicchia M. Is ozone pre-conditioning effect linked to Nrf2/EpRE activation pathway in vivo. A preliminary result? Eur J Pharmacol. 2014;742:158–162.

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Copyright (c) 2019 Abramov K.S., Davydova E.V., Osikov M.V., Kochengina S.A.

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