Modeling the Effect of Surface Modification of Gold Nanoparticles Irradiated with 60Co on the Secondary Рarticles Emission Spectrum


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The Monte Carlo method (computer simulation) is used to construct a physical model of secondary particles emission induced by the simulated irradiation of a gold nanoparticle with 60Co. It is demonstrated that the modification of the nanoparticle surface with polyethylene glycol affects the spectrum of secondary electrons produced in a nanoparticle and leaving it and its shell. The model takes into account the size and the chemical composition of the shell and provides an opportunity to design antitumor radiosensitizers based on gold nanoparticles.

作者简介

A. Belousov

Department of Physics

Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 119991

V. Morozov

Department of Physics; Burnazyan Federal Medical Biophysical Center

编辑信件的主要联系方式.
Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 119991; Moscow, 123182

G. Krusanov

Skobeltsyn Institute of Nuclear Physics

Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 119991

M. Kolyvanova

Burnazyan Federal Medical Biophysical Center

Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 123182

A. Chernyaev

Department of Physics; Skobeltsyn Institute of Nuclear Physics

Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 119991; Moscow, 119991

A. Shtil

Blokhin National Medical Oncology Research Center

Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 115478

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