Modeling the Effect of Surface Modification of Gold Nanoparticles Irradiated with 60Co on the Secondary Рarticles Emission Spectrum
- 作者: Belousov A.V.1, Morozov V.N.1,2, Krusanov G.A.3, Kolyvanova M.A.2, Chernyaev A.P.1,3, Shtil A.A.4
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隶属关系:
- Department of Physics
- Burnazyan Federal Medical Biophysical Center
- Skobeltsyn Institute of Nuclear Physics
- Blokhin National Medical Oncology Research Center
- 期: 卷 63, 编号 3 (2018)
- 页面: 96-99
- 栏目: Physics
- URL: https://journals.rcsi.science/1028-3358/article/view/192744
- DOI: https://doi.org/10.1134/S1028335818030059
- ID: 192744
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详细
The Monte Carlo method (computer simulation) is used to construct a physical model of secondary particles emission induced by the simulated irradiation of a gold nanoparticle with 60Co. It is demonstrated that the modification of the nanoparticle surface with polyethylene glycol affects the spectrum of secondary electrons produced in a nanoparticle and leaving it and its shell. The model takes into account the size and the chemical composition of the shell and provides an opportunity to design antitumor radiosensitizers based on gold nanoparticles.
作者简介
A. Belousov
Department of Physics
Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 119991
V. Morozov
Department of Physics; Burnazyan Federal Medical Biophysical Center
编辑信件的主要联系方式.
Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 119991; Moscow, 123182
G. Krusanov
Skobeltsyn Institute of Nuclear Physics
Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 119991
M. Kolyvanova
Burnazyan Federal Medical Biophysical Center
Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 123182
A. Chernyaev
Department of Physics; Skobeltsyn Institute of Nuclear Physics
Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 119991; Moscow, 119991
A. Shtil
Blokhin National Medical Oncology Research Center
Email: morozov.v.n@mail.ru
俄罗斯联邦, Moscow, 115478
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