Peculiarties of catecholamines exchange in children with febrile convulsions

Excretion of catecholamines indiumal urine of 75 children with febrile convulsionns has been studied. It has been revealed that functional state of sympathetic adrenal system in children with febrile convulsions is characterized by a number of peculiarities. They include an increase of adrenaline and norepinephrine. In the case of transformation of febrile into afebrile seizures additional increase of dopamine excretion is observed. That’s why hypersecretion of the three mentioned amines is estimated as prognostically unfavourable factor of the course of febrile convulsions. According to our findings, progression of seizures in sleeping state is also prognostically unfavourable symptom of the course of febrile seizures. The obtained biochemical ringings together with clinical information can serve as prognostic criteria in solving the problem of variations of the course of febrile convulsions.