Is a new one a well forgotten old? Sleep deprivation as a method of therapy for depression. Part I

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Abstract

The large amount of clinical data on the efficacy and safety of the sleep deprivation technique and its neurobiological mechanisms of action suggest that this technique can be employed as one of mood disorders treatment strategies and used as a biological method of first-line thymoanaleptic therapy. The aim of using sleep deprivation in the clinical setting is to relieve depressive syndrome and to prevent relapses, especially in the cases when patients are resistant for pharmacotherapy. In the modern society, sleep deprivation represents an alternative to the use of traditional approaches in the treatment of depression. In part I of this review we focus on indications for this method, protocols of therapeutic sessions, and well as on the amount of time spent on sleep deprivation needed for achievement of therapeutic effect.

About the authors

Andrey V. Antsyborov

Rostov State Medical University; Мedical center “South-Clinics”

Author for correspondence.
Email: andrei.v.ancyborov@gmail.com
ORCID iD: 0000-0001-6175-9545

аспирант кафедры психиатрии

Russian Federation, 344022, Rostov-on-Don, Nakhichevan lane, 29; 344002, Rostov-on-Don, Budennovsky Avenue, 6

Irina V. Dubatova

Rostov State Medical University

Email: tory15@mail.ru
Russian Federation, 344022, Rostov-on-Don, Nakhichevan lane, 29

Anna V. Kalinchuk

Мedical center “South-Clinics”; Southern Scientific Centre of the Russian Academy of Sciences

Email: avk@sleep-161.science

PhD, Senior Research Scientist

Russian Federation, 344002, Rostov-on-Don, Budennovsky Avenue, 6; 344006, Rostov-on-Don, Chekhov Avenue, 41

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Copyright (c) 2021 Antsyborov A.V., Dubatova I.V., Kalinchuk A.V.

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