Metabolic 99mTc-1-Thio-D-Glucose SPECT/CT in the Diagnosis of Brain Metastasis of Genital Diffuse-B-Large Cell Lymphoma (Clinical Case)
- Authors: Muravleva A.V.1, Goldberg V.E.1, Dudnikova E.A.1, Kravchuk T.L.1, Zelchan R.V.1, Medvedeva A.A.1, Bragina O.D.1, Simolina E.I.1, Popova N.O.1, Vysockaja V.V.1, Shatalova V.A.1, Rybina A.N.1, Goldberg A.V.1, Tabakaev S.A.1, Chernov V.I.1
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Affiliations:
- Cancer Research Institute, Tomsk National Research Medical Center
- Issue: Vol 68, No 4 (2023)
- Pages: 81-84
- Section: Nuclear Medicine
- URL: https://journals.rcsi.science/1024-6177/article/view/363855
- DOI: https://doi.org/10.33266/1024-6177-2023-68-4-81-84
- ID: 363855
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Abstract
Purpose: To demonstrate a rare clinical case of early recurrence of verified primary genital lymphoma and the possibility of 99mTc-1-Thio-D-glucose (99mTc-TG) SPECT/CT using to brain metastasis diagnosis.
Material and methods: A patient with a diagnosis of primary diffuse large B-cell genital lymphoma underwent magnetic resonance imaging (MRI) to assess the extent of the disease. Post-treatment follow-up included 18F-FDG PET/CT. To diagnose brain metastasis, 99mTc-TG SPECT/CT and MRI were performed.
Results: A rare case of early recurrence of diffuse large B-cell lymphoma with a primary local lesion in the genital organs is described. The possibility of modern methods of nuclear medicine in the diagnosis of early recurrence of malignant lymphoma has been demonstrated. 99mTc-TG SPECT/CT and MRI, were useful for visualization of a high metabolic brain tumor at the outpatient stage and recommendation of high-dose therapy according to the scheme MT-R was done.
Conclusion: The article presents a rare clinical case of early recurrence of diffuse large B-cell genital lymphoma. Possibilities of SPECT/CT with 99mTc-TG for visualization of lymphoma metastasis to the brain were demonstrated.
About the authors
A. V. Muravleva
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
V. E. Goldberg
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
E. A. Dudnikova
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
T. L. Kravchuk
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
R. V. Zelchan
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
A. A. Medvedeva
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
O. D. Bragina
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
E. I. Simolina
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
N. O. Popova
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
V. V. Vysockaja
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
V. A. Shatalova
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
A. N. Rybina
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
A. V. Goldberg
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
S. A. Tabakaev
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
V. I. Chernov
Cancer Research Institute, Tomsk National Research Medical Center
Email: albina_danilova7487@mail.ru
Tomsk
References
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