Synthesis of La3+/Co3O4 Nanoflowers for Sensitive Detection of Chlorpromazine


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Abstract

In this study, a sensitive electrochemical sensor for chlorpromazine was established based on La3+/Co3O4 nanoflower. The La3+/Co3O4 nanoflower exhibited superior electrochemical activity towards the oxidation of chlorpromazine. Electrochemical oxidation of chlorpromazine on the modified electrode was an diffusion-controlled process. Electrochemical oxidation peak currents linearly increased with chlor-promazine concentrations in the range of 0.5 and 400.0 μM. The detection limit was calculated as 0.08 μM. The La3+/Co3O4/GCE allowed to determine the chlorpromazine in real samples. The results indicated that the electrochemical sensor prepared in this study could be a very promising alternative to current analytical methods used to determine chlorpromazine.

About the authors

Somayeh Tajik

Research Center for Tropical and Infectious Diseases

Author for correspondence.
Email: Tajik_s1365@yahoo.com
Iran, Islamic Republic of, Kerman

Farib Garkani-Nejad

Research Center for Tropical and Infectious Diseases; Environment Department, Institute of Science and High Technology and Environmental Sciences

Author for correspondence.
Email: f.garkani95@gmail.com
Iran, Islamic Republic of, Kerman; Kerman

Hadi Beitollahi

Environment Department, Institute of Science and High Technology and Environmental Sciences

Email: f.garkani95@gmail.com
Iran, Islamic Republic of, Kerman

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