High Allelic Diversity of the DRB3 Gene (MHC Class II) in Saiga (Saiga tatarica) L., 1766), Obtained by Next Generation Sequencing Method
- 作者: Tarasyan K.1, Sorokin P.1, Kashinina N.1, Kholodova M.1,2
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隶属关系:
- Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences
- Department of Zoology, Tomsk State University
- 期: 卷 55, 编号 2 (2019)
- 页面: 212-219
- 栏目: Animal Genetics
- URL: https://journals.rcsi.science/1022-7954/article/view/189239
- DOI: https://doi.org/10.1134/S1022795419020133
- ID: 189239
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详细
The nucleotide sequences of the alleles of the DRB3 gene of the major histocompatibility complex (class II) of saiga antelope are described. A high degree of heterozygosity is found. The results of the analysis are consistent with the hypothesis of overdominance of heterozygotes. Phylogenetic relations of the DRB3 gene alleles of the saiga antelope and other Bovidae species do not correspond to the systematic position of Saiga tatarica. It is assumed that the polymorphism of the DRB3 gene alleles of saiga is primarily due to the variety of extracellular pathogens (bacteria, protozoa, helminths, and others) affecting its population during the evolutionary history of the species.
作者简介
K. Tarasyan
Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences
Email: sorokin-p@yandex.ru
俄罗斯联邦, Moscow,, 119071
P. Sorokin
Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: sorokin-p@yandex.ru
俄罗斯联邦, Moscow,, 119071
N. Kashinina
Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences
Email: sorokin-p@yandex.ru
俄罗斯联邦, Moscow,, 119071
M. Kholodova
Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences; Department of Zoology, Tomsk State University
Email: sorokin-p@yandex.ru
俄罗斯联邦, Moscow,, 119071; Tomsk, 634050