Molecular Genetic Studies of Cognitive Ability


Citar

Texto integral

Acesso aberto Acesso aberto
Acesso é fechado Acesso está concedido
Acesso é fechado Somente assinantes

Resumo

The paper presents a review of the results of molecular genetic studies of cognitive abilities. To date, a small number of genes responsible for normal cognitive functioning have been detected despite numerous studies based on the approach of candidate genes, genome-wide association studies, and linkage analyses. It should be considered that, even when the genetic variants were significantly associated with cognitive phenotypes, the sizes of the effect were usually very low (1–2%). However, large-scale genetic studies performed in the last few years significantly expanded the knowledge on the molecular basis of human cognitive abilities and made it possible to explain up to 20% of the 50% inheritance of intelligence.

Sobre autores

S. Malykh

Psychological Institute, Russian Academy of Education; Moscow State University

Autor responsável pela correspondência
Email: malykhsb@mail.ru
Rússia, Moscow, 125009; Moscow, 119991

A. Malykh

National Research Nuclear University (Moscow Engineering Physics Institute); Moscow State University

Email: carunas@list.ru
Rússia, Moscow, 115409; Moscow, 119991

A. Karunas

Institute of Biochemistry and Genetics, Ufa Federal Research Center, Russian Academy of Sciences

Autor responsável pela correspondência
Email: carunas@list.ru
Rússia, Ufa, 450054

R. Enikeeva

Institute of Biochemistry and Genetics, Ufa Federal Research Center, Russian Academy of Sciences

Email: carunas@list.ru
Rússia, Ufa, 450054

Y. Davydova

Institute of Biochemistry and Genetics, Ufa Federal Research Center, Russian Academy of Sciences

Email: carunas@list.ru
Rússia, Ufa, 450054

E. Khusnutdinova

Institute of Biochemistry and Genetics, Ufa Federal Research Center, Russian Academy of Sciences; Moscow State University

Email: carunas@list.ru
Rússia, Ufa, 450054; Moscow, 119991

Arquivos suplementares

Arquivos suplementares
Ação
1. JATS XML

Declaração de direitos autorais © Pleiades Publishing, Inc., 2019