Отправить статью по E-mail Development of Multiplex Genotyping Method of Polymorphic Markers of Genes Associated with Cognitive Abilities
- Авторы: Vagaitseva K.1,2, Bocharova A.1, Marusin A.1, Kolesnikova E.2, Makeeva O.1,3, Stepanov V.1,2
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Учреждения:
- Research Institute of Medical Genetics
- National Research Tomsk State University
- Center for Clinical Trials
- Выпуск: Том 54, № 6 (2018)
- Страницы: 740-745
- Раздел: Methods
- URL: https://journals.rcsi.science/1022-7954/article/view/189036
- DOI: https://doi.org/10.1134/S1022795418060121
- ID: 189036
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Аннотация
A developed method of multiplex genotyping of polymorphic markers of genes associated with cognitive abilities and neuropsychiatric diseases is based on multilocus PCR and MALDI-TOF mass spectrometry of DNA molecules. The frequencies of 32 single-nucleotide markers localized in 24 genes are analyzed in a sample of elderly people from the Russian population of Tomsk. The data obtained are compared with data for populations from the 1000 Genomes Project.
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Об авторах
K. Vagaitseva
Research Institute of Medical Genetics; National Research Tomsk State University
Автор, ответственный за переписку.
Email: kseniya.simonova@medgenetics.ru
Россия, Tomsk, 634050; Tomsk, 634050
A. Bocharova
Research Institute of Medical Genetics
Email: kseniya.simonova@medgenetics.ru
Россия, Tomsk, 634050
A. Marusin
Research Institute of Medical Genetics
Email: kseniya.simonova@medgenetics.ru
Россия, Tomsk, 634050
E. Kolesnikova
National Research Tomsk State University
Email: kseniya.simonova@medgenetics.ru
Россия, Tomsk, 634050
O. Makeeva
Research Institute of Medical Genetics; Center for Clinical Trials
Email: kseniya.simonova@medgenetics.ru
Россия, Tomsk, 634050; Tomsk, 634009
V. Stepanov
Research Institute of Medical Genetics; National Research Tomsk State University
Email: kseniya.simonova@medgenetics.ru
Россия, Tomsk, 634050; Tomsk, 634050
