Genotoxic and Carcinogenic Effects of Industrial Factors in Coal Mining and Coal-Processing Industry (Review)

Resumo

This paper presents a review of research devoted to the study of genotoxic and carcinogenic effects of exposure to factors of the production environment of the coal mining and coal processing industries. The first part of the review analyzes mutagenic effects: chromosomal aberrations (CA), sister chromatid exchanges (SCE), micronuclei (MN), and DNA comets in coal mining workers (mines) and workers in coal processing (coal heating plants, coking plants) enterprises. The second part is devoted to the study of cancer incidence in workers employed in the coal industry. The third part deals with works that carried out a comprehensive analysis of the mutagenic and carcinogenic effects in miners and workers at coal-fired power plants and coking plants. In general, the analysis of the literature confirmed the high genotoxic and carcinogenic danger of the working conditions for workers employed in the coal mining and coal processing industry.