Genetic factors in the development of chronic kidney disease in patients with diabetes mellitus

O. K. Vikulova; A. V. Zheleznyakova; N. O. Lebedeva; A. G. Nikitin; V. V. Nosikov; M. V. Shestakova

doi:10.1134/S1022795417030140

Genetic factors in the development of chronic kidney disease in patients with diabetes mellitus

Authors: Vikulova O.K.¹^,2, Zheleznyakova A.V.¹, Lebedeva N.O.¹, Nikitin A.G.³, Nosikov V.V.³, Shestakova M.V.¹^,2
Affiliations:
1. Endocrinology Research Centre
2. Sechenov First Moscow State Medical University
3. Federal Research Clinical Center
Issue: Vol 53, No 4 (2017)
Pages: 420-432
Section: Review and Theoretical Articles
URL: https://journals.rcsi.science/1022-7954/article/view/188197
DOI: https://doi.org/10.1134/S1022795417030140
ID: 188197

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Abstract

Patients with diabetes mellitus (DM) represent a risk group for developing chronic kidney disease (CKD), the terminal stages of which require renal replacement therapy. The study of genetic predisposition to CKD is of special significance from the perspective of the prediction and identification of risk groups at the preclinical stage. The present study is a review of the world literature on the genetics of CKD in diabetes and also includes data of our own studies.