Genetic and Genomic Basis of Aggressive Behavior

Resumo

Genetic and genomic studies of aggressive behavior are of great interest both for clinical medicine, which is related to treatment of patients with various forms of personality and psychiatric disorders, and for forensic purposes, in particular, for prognostication of different types of crime. Moreover, genetic research of aggressive behavior has major importance in connection to social and familial relationships, dealing with relations to children in society and family. Numerous studies have been published in this field. The present review describes studies on the genetic basis of aggressive/antisocial behavior, genome wide associations, and meta-analyses. The problems of genotype–social environment interaction and epigenetic mechanisms of genotype implementation in humans are discussed.