Genotyping of Bacillus anthracis and Closely Related Microorganisms
- Authors: Timofeev V.S.1, Bakhteeva I.V.1, Dyatlov I.A.1
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Affiliations:
- State Research Center of Applied Microbiology and Biotechnology
- Issue: Vol 54, No 1 (2018)
- Pages: 1-11
- Section: Reviews and Theoretical Articles
- URL: https://journals.rcsi.science/1022-7954/article/view/188748
- DOI: https://doi.org/10.1134/S1022795418010118
- ID: 188748
Cite item
Abstract
Bacillus cereus sensu lato group, which includes the causative agent of anthrax Bacillus anthracis, has a high degree of genetic similarity. However, in recent years, the development of molecular genetics has made it possible to find some molecular markers for identifying Bacillus anthracis in order to differentiate it from the closely related bacilli, get the clustering of the collection of strains, and describe the phylogenetic relationships between the clusters. This article deals with up-to-date methods of genotyping of Bacillus anthracis; it also evaluates its discrimination ability, informational value, validity of the results, efficiency, simplicity, and ease of use. In addition, international online resources and the possibility of their use for comparing collections of the B. anthracis strains isolated from various parts of the world are discussed.
Keywords
About the authors
V. S. Timofeev
State Research Center of Applied Microbiology and Biotechnology
Author for correspondence.
Email: timofeev@obolensk.org
Russian Federation, Obolensk, Moscow oblast, 142279
I. V. Bakhteeva
State Research Center of Applied Microbiology and Biotechnology
Email: timofeev@obolensk.org
Russian Federation, Obolensk, Moscow oblast, 142279
I. A. Dyatlov
State Research Center of Applied Microbiology and Biotechnology
Email: timofeev@obolensk.org
Russian Federation, Obolensk, Moscow oblast, 142279