Email this article 31P NMR Manifestation of Metabolic Changes in Blood of Spinal Cord Injured Rats
- Authors: Yurtaeva S.V.1, Volkov M.Y.1, Yafarova G.G.1,2, Silantyeva D.I.2, Yamalitdinova E.I.2
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Affiliations:
- Kazan Physical-Technical Institute, KSC, RAS
- Institute of Fundamental Medicine and Biology, Kazan Federal University
- Issue: Vol 49, No 4 (2018)
- Pages: 389-401
- Section: Original Paper
- URL: https://journals.rcsi.science/0937-9347/article/view/248521
- DOI: https://doi.org/10.1007/s00723-018-0982-5
- ID: 248521
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Abstract
The 31P nuclear magnetic resonance spectroscopy technique was applied to study the blood of rats with a 3-day spinal cord injury and control rats. Phosphorus-containing blood metabolites: 2,3-diphosphoglycerates, inorganic phosphates, phospholipids, ATP and adenosine monophosphates were detected and quantitatively evaluated. It was found that the amount of 2,3-diphosphoglycerates, inorganic phosphates, phospholipids and adenosine monophosphates increase, and pH of the blood decreases after spinal cord injury. The results demonstrate increased hypoxia in injured rats.
About the authors
S. V. Yurtaeva
Kazan Physical-Technical Institute, KSC, RAS
Author for correspondence.
Email: s.yurtaeva@kfti.knc.ru
Russian Federation, Kazan
M. Yu. Volkov
Kazan Physical-Technical Institute, KSC, RAS
Email: s.yurtaeva@kfti.knc.ru
Russian Federation, Kazan
G. G. Yafarova
Kazan Physical-Technical Institute, KSC, RAS; Institute of Fundamental Medicine and Biology, Kazan Federal University
Email: s.yurtaeva@kfti.knc.ru
Russian Federation, Kazan; Kazan
D. I. Silantyeva
Institute of Fundamental Medicine and Biology, Kazan Federal University
Email: s.yurtaeva@kfti.knc.ru
Russian Federation, Kazan
E. I. Yamalitdinova
Institute of Fundamental Medicine and Biology, Kazan Federal University
Email: s.yurtaeva@kfti.knc.ru
Russian Federation, Kazan
