Pathophysiological mechanisms of the consequences of trauma of the musculoskeletal system

In the most general form, the main factors of traumatic disease can be represented as follows (Scheme 1): the traumatic factor acts on organs and tissues, causing their damage. As a result of this, the cells are destroyed and their contents are released into the intercellular environment; other cells are exposed to concussion, as a result of which their metabolism and their inherent functions are disturbed. Primarily (as a result of the action of a traumatic factor) and secondarily (due to a change in the tissue environment), numerous receptors in the wound are irritated, which is subjectively perceived as pain, and objectively characterized by numerous reactions of organs and systems.