Russian Experience in Rational Thromboprophylaxis in Traumatology and Orthopaedics


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Abstract

Analysis of safety and efficacy of the currently marked peroral anticoagulants was performed in long term follow up of patients after large joints arthroplasty. Total number of 5025 patients after total knee arthroplasty and 5216 patients after total hip arthroplasty were examined. All patients were divided into groups depending on the prescribed anticoagulant. The course of anticoagulant therapy made up 35 days and 6 weeks after surgery, respectively. US examination of the veins of lower extremities was performed to all patients prior to and on day 5 after operation. In patients on Dabigatran the rate of clinically significant deep vein thrombosis was lower than in group of patients on Rivaroxaban and Apixaban, but the rate of postoperative hematomas in lust two groops was higher.

About the authors

S. A Firsov

Yaroslavl’ Railway Clinical Hospital, Center of Traumatology and Orthopaedics, Yaroslavl’

Email: serg375@yandex.ru
доктор мед. наук, руководитель Центра травматологии и ортопедии; Тел.: +7 (910) 973-79-81 150000, Ярославль, ул. Суздальское шоссе, д. 21

A. G Levshin

Yaroslavl’ Railway Clinical Hospital, Center of Traumatology and Orthopaedics, Yaroslavl’

врач травматолог-ортопед Центра травматологии и ортопедии

R. P Matveev

Northern State Medical University, Arkhangel’sk, Russia

доктор мед. наук, зав. кафедрой травматологии, ортопедии и военной хирургии СГМУ

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