Experience with the use of bioactive calcium phosphate-coated implants in multicomponent traumatic damage to the hip joint

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Abstract

Objective. To study the effectiveness of using implants with a bioactive calcium-phosphate coating on the example of treating a patient with combined fractures of the acetabulum and the neck of the femur.

Materials and methods. A 52-year-old patient, injured as a result of a traffic accident with multicomponent damage to the right hip joint (transcervical fracture of the femoral neck and a high two-column fracture of the acetabulum). Osteosynthesis of the femoral neck fracture is made by three cannulated screws with a calcium-phosphate coating (patent of the RU No. 81427). For the osteosynthesis of the acetabular fracture, a reconstructive plate with a calcium-phosphate coating was used (patent of the RU No. 113945).

Results. Despite the heavy, multi-component destruction of the hip joint, consolidation of the fractures ensued. The remote result is tracked for 10 years. On the score scale of the functional results Harris 89 points, the result is rated as good.

The conclusion. The use of imantates with bioactive calcium-phosphate coatings from hydroxyapatite promotes activation of reparative processes in the region of fractures.

About the authors

Alexey A. Grin

Tyumen State Medical University; Regional Hospital No. 3 of Tobolsk

Email: danilovaav.2000@mail.ru

MD, associate professor of the department of traumatology and orthopedics with the course of children’s traumatology INPR, doctor of the highest category traumatologist-orthopedist, head of the traumatologist-orthopedic department

Russian Federation, Tyumen; Tobolsk

Alexander A. Markov

Tyumen State Medical University

Email: danilovaav.2000@mail.ru

MD, associate professor of the department of traumatology and orthopedics with the course of children’s traumatology INPR

Russian Federation, Tyumen

Anastasiya V. Danilova

Tyumen State Medical University; Regional Clinical Hospital No. 2

Author for correspondence.
Email: danilovaav.2000@mail.ru

clinical resident of the second year of study of the department of traumatology and orthopedics with the course of children’s traumatology INPR, traumatologist-orthopedist

Russian Federation, Tyumen; Tyumen

Konstantin S. Sergeev

Tyumen State Medical University

Email: danilovaav.2000@mail.ru

PhD, professor, head of the department of traumatology and orthopedics with the course of children’s traumatology INPR

Russian Federation, Tyumen

References

  1. Ежов Ю.И., Смирнов А.А., Лабазин А.Л. Диагностика и лечение краевых переломов вертлужной впадины. Вестник травматологии и ортопедии им. Н.Н. Приорова. 2003;(3):72-74. [Ezhov YuI, Smirnov AA, Labazin AL. Diagnosis and treatment of marginal acetabular fractures. Vestnik travmatologii i ortopedii im. N.N. Priorova. 2003;(3):72-74. (In Russ.)]
  2. Канзюба А.И. Внутренний остеосинтез при переломах вертлужной впадины. Травма. 2006;7(4):274-281. [Kanzyuba AI. Internal osteosynthesis for acetabular fractures. Travma. 2006;7(4):274-281. (In Russ.)]
  3. Солод Э.И., Лазарев А.Ф., Сахарных И.Н., Стоюхин С.С. Новые технологии остеосинтез переломов вертлужной впадины. Медицинский алфавит. 2014;2(11):6-10. [Solod EI, Lazarev AF, Sakharnykh IN, Stoyukhin SS. Novye tekhnologii osteosintez perelomov vertluzhnoi vpadiny. Meditsinskii alfavit. 2014;2(11):6-10. (In Russ.)]
  4. Гильфанов С.И., Ключевский В.В., Данилюк В.В. Оперативное лечение переломов вертельной области. Вестник травматологии и ортопедии им. Н.Н. Приорова. 2005;(4):19-22. [Gilfanov SI, Klyuchevskiy VV, Danilyuk VV. Operative treatment of trochanteric fractures. Vestnik travmatologii i ortopedii im. N.N. Priorova. 2005;(4):19-22. (In Russ.)]
  5. Parker MJ, White A, Boyle A. Fixation versus hemiarthroplasty for undisplaced intracapsular hip fractures. Injury. 2008;39(7):791-795. https://doi.org/10.1016/j.injury.2008.01.011.
  6. Letournel E, Judet R, Elson RA, ed. Fractures of the Acetabulum. 2nd ed. Berlin: Spring-er-Verlag; 1993. P. 27-28, 346-350, 358-359, 363-397. https://doi.org/10.1007/978-3-642-75435-7_21.
  7. Masoud R, Bizouarn T, Trepout S, et al. Titanium dioxide nanoparticles increase superoxide anion production by acting on NADPH oxidase. PLoS One. 2015;10(12):e0144829. https://doi.org/10.1371/journal.pone.0144829.
  8. Kim HT, Ahn JM, Hur JO, et al. Reconstruction of acetabular posterior wall fractures. Clin Orthop Surg. 2011;3(2):114-120. https://doi.org/10.4055/cios.2011.3.2.114.
  9. Song L, Tian Q, Liu Y, Shao Z, Yang S. Mid- and long-term clinical effects of trochanteric flip osteotomy for treatment of pipkin I and II femoral head fractures. Nan Fang Yi Ke Da Xue Xue Bao. 2013;33(9):1260-1264.
  10. Лобанов Г.В., Прудников Ю.В. Результаты оперативного лечения больных с переломами задней стенки вертлужной впадины, леченных традиционным способом с использованием хирургического доступа Кохера – Лангенбека. Травма. 2013;14(3):9-12. [Lobanov GV, Prudnikov YuV. Outcomes of surgical treatment of patients with posterior acetabular wall fractures treated in the traditional way, using Kocher–Langenbeck surgical approach. Travma. 2013;14(3):9-12. (In Russ.)]
  11. Batra S, Batra M, McMurtrie A, Sinha AK. Rapidly destructive osteoarthritis of the hip joint: a case series. J Orthop Surg Res. 2008;3:3. https://doi.org/10.1186/1749-799X-3-3.
  12. Seo GS, Dieudonne G, Mooney SA, Monu JU. Unexplained «massive osteolysis of femoral head» (MOFH) after acetabular fracture: occurrence and suggested patho-etiology. Acta Radiol. 2017;58(6):710-718. https://doi.org/10.1177/0284185116665422.
  13. Бондаренко А.В., Плотников И.А. Сравнительный анализ методов оперативного лечения переломоввертельной области у пациентов с политравмой. Политравма. 2011;(1):12-17. [Bondarenko AV, Plotnikov IA. The comparative analysis of surgical treatment of trochanteric fractures in patients with polytrauma. Polytravma. 2011;(1):12-17. (In Russ.)]
  14. Solberg BD, Moon CN, Franco DP. Use of a trochanteric flip osteotomy improves outcomes in pipkin IV fractures. Clin Orthop Relat Res. 2009;467(4):929-933. https://doi.org/10.1007/s11999-008-0505-z.
  15. Winquist RA. Locked femoral nailing. J Am Acad Orthop Surg. 1993;1(2):95-105. https://doi.org/10.5435/00124635-199311000-00004.
  16. Артюх В.А. Разработка усовершенствованных подходов к хирургическому лечению больных с переломами вертлужной впадины и их последствиями: Автореф. дис. ... канд. мед. наук. — СПб.; 2007. — 24с. [Artyukh VA. Razrabotka usovershenstvovannykh podkhodov k khirurgicheskomu lecheniyu bol’nykh s perelomami vertluzhnoĭ vpadiny i ikh posledstviyami. [dissertation abstract] St. Petersburg; 2007. 24 p. (In Russ.)] Available at: https://rusneb.ru/catalog/000200_000018_RU_NLR_bibl_1206373/.
  17. Буачидзе О.Ш., Волошин В.П., Зубков В.С., и др. Тотальное замещение тазобедренного сустава при тяжелых последствиях его повреждений. Вестник травматологии и ортопедии им. Н.Н. Приорова. 2004;(2):13-17. [Buachidze OSh, Voloshin VP, Zubikov VS, et al. Total hip replacement in severe sequelae of its injury. Vestnik travmatologii i ortopedii im. N.N. Priorova. 2004;(2):13-17. (In Russ.)]
  18. Sadeghifar A, Saied A. Bilateral simultaneous femoral neck and shafts fractures — a case report. Arch Bone Joint Surg. 2014;2(4):268-271.
  19. Барабаш А.А., Барабаш А.П., Барабаш Ю.А., Алфимов Р.А. Замедленное костеобразование: пути решения проблемы. В кн.: Оптимизация лечения и реабилитации больных: труды общества травматологов-ортопедов Ростовской области. — Ростов н/Д: 2005. — C. 50-55. [Barabash AA, Barabash AP, Barabash YuA, Alfimov RA. Zamedlennoe kosteobrazovanie: puti resheniya problemy. In: Optimizatsiya lecheniya i reabilitatsii bol’nykh: trudy obshchestva travmatologov-ortopedov Rostovskoi oblasti. Rostov-na-Donu; 2005. P. 50-55. (In Russ.)]
  20. Карлов П.К., Погребенков В.М. Хирургическое устройство и керамический биоактивный материал для остеосинтеза. Патент RU № 2105529/ 27.02.1998. [Karlov PK, Pogrebenkov VM. Khirurgicheskoe ustroistvo i keramicheskii bioaktivnyi material dlya osteosinteza. Patent RU 2105529/ 27.02.1998. (In Russ.)] Available at: https://www1.fips.ru/
  21. Ахтямов И.Ф., Шакирова Ф.В., Гатина Э.Б., и др. Морфологическое исследование местного действия имплантата с твердой поверхностью при индуцированной травме. Гений ортопедии. 2015;(1):65-70. [Akhtiamov IF, Shakirova FV, Gatina EB, et al. A morphological study of the local effect of the implants with superhard-compound coatings on bone tissue under the conditions of induced trauma. Genii ortopedii. 2015;(1):65-70. (In Russ.)]
  22. Montanaro L, Testoni F, Poggi A, et al. Emerging pathogenetic mechanisms of the implant-related osteomyelitis by Staphylococcus aureus. Int J Artif Organs. 2011;34(9):781-788. https://doi.org/10.5301/ijao.5000052.
  23. Ляхов Н.З., ред. Биокомпозиты на основе кальций-фосфатных покрытий, наноструктурных и ультрамелкодисперсных биоинертных металлов, их биосовместимость и биодеградация. — Томск: ТГУ; 2014. [Lyakhov NZ, ed. Biokompozity na osnove kal’tsii-fosfatnykh pokrytii, nanostrukturnykh i ul’tramelkodispersnykh bioinertnykh metallov, ikh biosovmestimost’ i biodegradatsiya. Tomsk: TGU; 2014. (In Russ.)]
  24. Yang HW, Lin MH, Xu YZ, et al. Osteogenesis of bone marrow mesenchymal stem cells on strontium-substituted nano-hydroxyapatite coated roughened titanium surfaces. Int J Clin Exp Med. 2015;8(1):257-264.
  25. Wu K, Xu J, Liu M, et al. Induction of osteogenic differentiation of stem cells via a lyophilized microRNA reverse transfection formulation on a tissue culture plate. Int J Nanomedicine. 2013;8:1595-1607. https://doi.org/10.2147/ijn.s43244.
  26. El Moumni M, Schraven P, ten Duis HJ, Wendt K. Persistent knee complaints after retrograde unreamed nailing of femoral shaft fractures. Acta Orthop Belg. 2010;76(2):219-225.
  27. Гринь А.А., Белов В.А., Рабченюк М.А., и др. Социальные аспекты повреждений вертлужной впадины в городе Тюмень и на юге Тюменской области. Медицинская наука и образование Урала. 2011;12(4):129-131. [Grin AA, Belov VA, Rabchenjuk MA, et al. Social aspects of damages of cotyle in town Tyumen and on the south of the Tyumenskoy area. Meditsinskaya nauka i obrazovanie Urala. 2011;12(4):129-131. (In Russ.)]
  28. Буачидзе О.Ш., Оноприенко Г.А., Волошин В.П. Переломы вертлужной впадины и их оперативное лечение. Медицинский академический журнал. 2003;3(2):112-114. [Buachidze OSh, Onoprienko GA, Voloshin VP. Fractures of the acetabulum and surgical treatment. Meditsinskii akademicheskii zhurnal. 2003;3(2):112-114. (In Russ.)]
  29. Гринь А.А., Рунков А.В., Шлыков И.Л. Выбор оперативного доступа при лечении двухколонных переломов вертлужной впадины. Травматология и ортопедия России. 2014;(1):92-97. [Grin’ AA, Runkov AV, Shlykov IL. The choice of surgical approach in the treatment of two-column acetabular fractures. Travmatologiya i ortopediya Rossii. 2014;(1):92-97. (In Russ.)]

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Fig. 1. Patient B. X-ray images in direct projection (a), obturator projection (b), iliac projection (c), and CT of the right hip joint (d)

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3. Fig. 2. Control X-ray images of patient B.: direct projection (a), obturator projection (b), iliac projection (c)

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4. Fig. 3. Patient B. X-ray images of the right hip joint after an unsuccessful attempt to remove cannulated screws securing the femoral neck

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