Improvement of blood supply and structure of avascular spongy bone: experimental study

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Abstract

Model of avascular necrosis of the femoral head was induced bilaterally in the 52 hips (26 dogs). Immediately intertrochanteric osteotomy was done on 18 hips and 17 hips had autogenous muscle-pedicle bone graft. Seventeen were kept as controls. Intraosseous pressure was measured, the vascular architecture was studied, and histologic examination of the femoral heads was done at 4, 8, and 12 weeks. The authors consider that intertrochanteric osteotomy gives highly favorable effect on the structure of avascular femoral head and intravenous administration of nitroglycerin solution improves the intraosseous circulation.

About the authors

E. A. Nazarov

Ryazan State Medical University. I.P. Pavlova

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Ryazan

V. G. Papkov

Ryazan State Medical University. I.P. Pavlova

Email: info@eco-vector.com
Russian Federation, Ryazan

K. V. Filimonov

Ryazan State Medical University. I.P. Pavlova

Email: info@eco-vector.com
Russian Federation, Ryazan

A. A. Zubov

Ryazan State Medical University. I.P. Pavlova

Email: info@eco-vector.com
Russian Federation, Ryazan

References

  1. Агаджанян В.В., Замулин А.Д. //Хирургические способы лечения заболеваний и последствий повреждений крупных суставов: Сб. науч. трудов. — Саратов,1990. — С. 42—46.
  2. Назаров Е.А. //Ортопед. травматол. — 1987. — N 10. — С. 20—25.
  3. Назаров Е.А., Папков В.Г., Фокин А.А. //Там же. —1991. — N 8. — С. 26—30.
  4. Шаиро Э.И. //Там же. — 1968. — N 7. — С. 48—53.
  5. Ficat R.P. //J. Bone Jt Surg. — 1985. — Vol. 67B, N 1. — P. 3—9.
  6. Hungerford D.S. //Orthopade. — 1990. — Bd 19. — S. 219—223.

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2. Fig. 1. Dynamics of intraosseous pressure in the proximal femur of dogs. I, ANGBK; II — ANGBK + intertrochanteric osteotomy; III - ANGBK + bone autoplasty with a graft on a muscle pedicle.

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3. Fig. 2. Intraosseous contrast phlebogram 12 weeks after intertrochanteric osteotomy (a) and bone autoplasty with a graft on a muscle pedicle (b). Fig. 3. Radiographs of the proximal femur 12 weeks after bone autoplasty with a graft on a muscle pedicle (a) and intertrochanteric osteotomy (b).

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4. Fig. 4. Microphotogram of the preparation 8 weeks after osteoplastic surgery: decaying necrotic fragments of bone tissue. (In Fig. 4-6 stained with hematoxylin and eosin. Magnitude 80.)

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5. Fig. 5. Microphotogram of the preparation 12 weeks after intertrochanteric osteotomy: plethora of vessels of bone beams and bone marrow.

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6. Fig. 6. Microphotogram of the preparation 8 weeks after intertrochanteric osteotomy: a lively osteoblastic and osteoplastic reaction.

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