Conservative treatment of patients with Paget disease

The paper deals with results of conservative treatment of 96 patients with Paget’s disease with the national drugs, such as calcitrin and xidiphone which affect osseous metabolism. Positive results were achieved in the clinical, X-ray, biochemical pattern of the disease in most patients. This makes it possible to recommend the drugs for treatment. The advantages and disadvantages of the agents are determined. The efficiency of xidiphone therapy is regarded to be the most beneficial. It is suggested that complications may develop and progress in some cases even when there are marked positive shifts, which dictates the necessity of continuous monitoring of patients.