Specific features of complications of osteoplastic surgeries following chemical and radiation therapies of patients with malignant bone tumors

The paper analyzes the nature and specific features of complications following osteoplastic surgeries performed in various periods after radiation and chemical therapies. Early complications did not depend on the radiation dose and the postradiation therapeutical interval, which suggests that they are closer related to the operation itself. In late complications, there is a relationship between their frequency and the postradiation interval. There are differences in the nature of complications and their natural history, which are accounted for the specific impact of ionizing radiation on soft tissues. In particular, there is a late manifestation of a radiation reaction which runs acutely and which is hardly differentiated from routine inflammation. The parameters of longevity after organpreserving surgery cannot serve as criteria for survival rates since they are obtained in examining random samples.