Morphogenesis and Pathogenesis of Traumatic Infarction of Long Bone (experimental 13 studay)

Morphogenesis and pathogenesis of traumatic infarction of long bone was studied in experiment (45 rats and 8 dogs). Tibial osteotomy with section of great branches of the main nutritive arteria were performed. Morphogenic indices of pathologic changes were studied in terms from 3 hours to 60 days and physiologic indices of intraosseous hemodynamics were studied in terms from 10 min to 8 hours During the first hours after osteotomy extensive loci of blood supply occulusion of bone marrow and diaphysial cortex were detected in free fragment ends. Then those loci were transformed into diaphysial infarction. Occulusion loci increased up to the end of the first day after osteotomy, then they started to decrease. Infarctions in distal fragment were reliably more extensive than the infarctions in proximal fragment. Physiologic indices testified severe blood supply aggravation in free distal fragment end.