Use of Collapan for Plasty of Osteomyelitis Bone Defects

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Abstract

Use of biocomposed material Collapan (Company «Intermedapatit», Russia) for the filling of bone defects after sequestrectomy was evaluated in 92 patients with chronic osteomyelitis of different localization. In 76 patients surgical wounds healed by first intention, in 16 patients — by second intention. Four patients had recurrence of purulent process in the term from 4 to 18 months after operation. Morphologic and histologic study of tissue specimens obtained during reoperation showed that inserted collapan induced antibacterial background, served as the matrix of newly forming bone tissue and activated the osteogenesis.

About the authors

Z. I. Urazgildeev

Priorov Central Institute of Traumatology and Orthopedics

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Moscow

O. M. Bushuev

Priorov Central Institute of Traumatology and Orthopedics

Email: info@eco-vector.com
Russian Federation, Moscow

G. N. Berchenko

Priorov Central Institute of Traumatology and Orthopedics

Email: info@eco-vector.com
Russian Federation, Moscow

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2. Fig. 1. Formation of bone trabeculae containing hydroxyapatite inclusions. Postoperative period was 4 months.

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3. Fig. 2. Bone trabecula acquiring lamellar structure; residual hydroxyapatite particles detected. Postoperative period of 8 months.

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4. Fig. 3. Patient 3. 60 years old with chronic gunshot osteomyelitis of the lower third of the right femur.

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Copyright (c) 1998 Eco-Vector



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