About Primary Malignant Chondroblastoma

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Abstract

According to the WHO histological classification of tumors (1972), chondroblastoma of bone belongs to benign cartilage-forming tumors. However, later literature data indicate the possibility of its malignancy. T.P. Vinogradova mentions its malignant form along with benign chondroblastoma, noting that "each benign form of tumor, as a rule, has its malignant analogue". There are 20 cases of malignant chondroblastoma described in the world literature and there are brief mentions of another 8 such cases. The work of V.N. Burdygin, A.K. Morozov and S.I. Lipkin [1] reports 6 own observations, A.K. Morozov reports 8 malignant chondroblastomas out of 113 studied, the publication of S.I. Lipkin - about 13 malignant chondroblastomas and 3 clear cell chondrosarcomas, which probably arose on the basis of chondroblastoma malignancy; according to V.L. Kotov and S.I. Lipkin, in 13 of 225 patients with chondroblastoma the tumor was verified as malignant.

About the authors

A. B. Shavirin

Ryazan Regional Clinical Hospital; Priorov Central Institute of Traumatology and Orthopedics

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Ryazan; Moscow

S. I. Lipkin

Ryazan Regional Clinical Hospital; Priorov Central Institute of Traumatology and Orthopedics

Email: info@eco-vector.com
Russian Federation, Ryazan; Moscow

References

Supplementary files

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2. Fig. 1. Preoperative radiograph of the right knee joint: a nidus of destruction in the inner condyle of the tibia.

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3. Fig. 2. Histological structure of the removed tumor: sharply pronounced polymorphism and atypism of cells with preservation of the general type of chondroblastoma structure. Hematoxylin and eosin staining. Enl. 300.

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4. Fig. 3. X-ray of the right knee joint 3 years after surgery: no signs of tumor recurrence; engraftment and remodeling of autografts.

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Copyright (c) 1998 Eco-Vector



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