Influence of ABCB1 gene polymorphism on rivaroxaban pharmacokinetics
- 作者: Kazakov R.1, Rodina T.1, Melnikov E.1, Danko A.1, Muslimova O.1, Demchenkova E.1, Checha O.1, Mazerkina I.1, Belkov S.1, Prokofev A.1
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隶属关系:
- Scientific Centre for Expert Evaluation of Medicinal Products
- 期: 卷 26, 编号 6 (2020)
- 页面: 386-393
- 栏目: Clinical pharmacology and pharmaceuticals
- URL: https://journals.rcsi.science/0869-2106/article/view/65032
- DOI: https://doi.org/10.17816/0869-2106-2020-26-6-386-393
- ID: 65032
如何引用文章
详细
This article presents the comparison of the pharmacogenetic and pharmacokinetic testing results in patients with atrial fibrillation taking rivaroxaban. The role of ABCB1 gene polymorphism in the variability of the pharmacological response was assessed, and the possibility of personalized treatment using therapeutic drug monitoring was discussed.
作者简介
Ruslan Kazakov
Scientific Centre for Expert Evaluation of Medicinal Products
编辑信件的主要联系方式.
Email: rustic100@rambler.ru
ORCID iD: 0000-0003-0802-4229
PhD (Biol.)
俄罗斯联邦, 127051, MoscowTatyana Rodina
Scientific Centre for Expert Evaluation of Medicinal Products
Email: semina_tatiana@mail.ru
ORCID iD: 0000-0002-0528-3068
PhD (Chem.)
俄罗斯联邦, 127051, MoscowEvgeny Melnikov
Scientific Centre for Expert Evaluation of Medicinal Products
Email: evgueniy.melnikov@gmail.com
ORCID iD: 0000-0002-8993-4808
PhD (Pharm.)
俄罗斯联邦, 127051, MoscowAndrey Danko
Scientific Centre for Expert Evaluation of Medicinal Products
Email: andreida@mail.ru
ORCID iD: 0000-0002-2963-5312
MD, PhD
俄罗斯联邦, 127051, MoscowOlga Muslimova
Scientific Centre for Expert Evaluation of Medicinal Products
Email: muslimova@expmed.ru
ORCID iD: 0000-0003-1009-9609
MD, PhD
俄罗斯联邦, 127051, MoscowElena Demchenkova
Scientific Centre for Expert Evaluation of Medicinal Products
Email: demchenkova@expmed.ru
ORCID iD: 0000-0003-1972-4386
PhD (Pharm.)
俄罗斯联邦, 127051, MoscowOlga Checha
Scientific Centre for Expert Evaluation of Medicinal Products
Email: checha@expmed.ru
ORCID iD: 0000-0002-7900-1078
PhD (Biol.)
俄罗斯联邦, 127051, MoscowIrina Mazerkina
Scientific Centre for Expert Evaluation of Medicinal Products
Email: mazerkina@expmed.ru
ORCID iD: 0000-0002-3733-6822
MD, PhD
俄罗斯联邦, 127051, MoscowSergey Belkov
Scientific Centre for Expert Evaluation of Medicinal Products
Email: evgenol-cinc@mail.ru
ORCID iD: 0000-0002-5587-5918
MD, PhD, DSc, Professor
俄罗斯联邦, 127051, MoscowAlexey Prokofev
Scientific Centre for Expert Evaluation of Medicinal Products
Email: prokofiev@expmed.ru
ORCID iD: 0000-0001-7024-5546
MD, PhD, DSc, Professor
俄罗斯联邦, 127051, Moscow参考
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