电邮这篇文章 The restless legs' syndrome
- 作者: Kopishinskaya S.1, Gustov A.1, Radyuk M.2
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隶属关系:
- The Nizhniy Novgorod state medical academy of Minzdrav of Russia
- The Volgograd state medical university of Minzdrav of Russia
- 期: 卷 21, 编号 4 (2015)
- 页面: 53-56
- 栏目: Articles
- URL: https://journals.rcsi.science/0869-2106/article/view/38300
- DOI: https://doi.org/10.17816/rmj38300
- ID: 38300
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详细
The restless legs' syndrome or Willis-Ekbom disease is a wide-spread sensory-motor illness characterized by imperative wish to move legs and accompanied by dysesthesia. Until recently, restless legs' syndrome considered as a rare disease in view of poor recognizability of symptoms. The undiagnosed and untreated restless legs syndrome results in serious disorder of sleep. The physiopathology of restless legs syndrome is multi-factorial i.e. dysfunction of dopamine-ergic system, decreasing of iron in central nervous system, genetic susceptibility, disturbance of level of such neurotransmitters as hypocretins and endorphins, immune dysfunction, inflammation. The manifestations of restless legs' syndrome are sensory sensations and periodic movements in extremities during sleep of mode of flexion. The article presents main and additional criteria of restless legs' syndrome as well as associated signs of restless legs syndrome. The transdermal plaster rotigotine and pregabalin is a leader in pharmaceutical therapy.
作者简介
Svetlana Kopishinskaya
The Nizhniy Novgorod state medical academy of Minzdrav of Russia
Email: kopishinskaya@gmail.com
MD, PhD 603950 Nizhniy Novgorod, Russia
A. Gustov
The Nizhniy Novgorod state medical academy of Minzdrav of Russia603950 Nizhniy Novgorod, Russia
M. Radyuk
The Volgograd state medical university of Minzdrav of Russia400131 Volgograd, Russia
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