Oral microbiome

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This study aimed to analyze the characteristics of the oral microbiome in dental caries and inflammatory periodontal diseases based on available data in the modern literature. This article is based on the analysis of materials from international and Russian studies in the PubMed, CyberLeninka, and MedLine databases over the past 15 years. An imbalance in the oral microbiome can develop dental caries and periodontal diseases. Normally, the oral microbiome contains Firmicutes, Proteobacteria, Actinobacteria, Bacteroides, Fusobacterium, and Spirochetes. With dental caries, S. mutans, Atopobium, Propionibacterium, and Lactobacillus are determined. The presence of Veillonella, Porphyromonas gingivalis, Tannerella forsythia, Aggregatibacter actinomycetemcomitans, Treponema, and Prevotella in the oral microbiome is associated with periodontal disease. The oral microbiome database comprises comprehensive data that describe bacterial species and the 16S rRNA that define the set of oral microbes. The microbiome is influenced by local and general factors.

作者简介

Igor Kopetsky

N.I. Pirogov Russian National Research Medical University

Email: kopetski@rambler.ru
ORCID iD: 0000-0002-4723-6067

MD, Dr. Sci. (Med.), Professor

俄罗斯联邦, Moscow

Ludmila Pobozhieva

N.I. Pirogov Russian National Research Medical University

Email: ludmila-stomatolog@mail.ru
ORCID iD: 0000-0002-6150-0282

MD, Cand. Sci. (Med.), assistant professor

俄罗斯联邦, Moscow

Alena Kopetskaya

N.I. Pirogov Russian National Research Medical University

编辑信件的主要联系方式.
Email: alyonasom@gmail.ru
ORCID iD: 0000-0003-3199-5314
俄罗斯联邦, Moscow

Julia Shevelyuk

I.M. Sechenov First Moscow Medicine State University

Email: shevelyuk_yu_v@staff.sechenov.ru
ORCID iD: 0000-0002-3854-456X

MD, Cand. Sci. (Med.), assistant lecturer

俄罗斯联邦, Moscow

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版权所有 © Kopetsky I.S., Pobozhieva L.V., Kopetskaya A.I., Shevelyuk J.V., 2021

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