Experiences of testing immunoglobulins to the SARS-CoV-2 virus in outpatient practice

The study aimed to analyze the results of testing the presence of immunoglobulins of severe acute respiratory syndrome coronavirus 2 infection in outpatient clinical practice. The data of all tests of immunoglobulins G and M performed in the laboratory of Polyclinic No. 2 of the Administrative Department of the President of the Russian Federation from June 5 to October 2, 2020, were analyzed. In total, the studies were conducted in 784 applicants (319 [40.7%] men and 465 [59.3%] women), with the average age of 48.46±14.044 years (18 to 89 years). Of patients, 317 were clinically diagnosed with a new coronavirus infection, 64 were examined as having contacted the infected, 83 had bronchopulmonary diseases, and 320 were healthy individuals. A positive test result for the presence of IgG antibodies was obtained in 87.7% of patients with a new coronavirus infection. Of cases, 96.3% had a typical X-ray presentation of viral pneumonia that was confirmed by the polymerase chain reaction method, and also, 5% of cases in the healthy group. The data obtained enabled us to establish high sensitivity of the test systems used.