Email this article THE COMPLEX REGIONAL PAIN SYNDROME
- Authors: Damulin I.V.1,2, Galaeva A.A1
-
Affiliations:
- The I.M. Sechenov first Moscow state medical university of the Ministry of Health of the Russian Federation
- The Moscow clinical scientific practical center of the Moscow Health Department
- Issue: Vol 24, No 2 (2018)
- Pages: 104-108
- Section: Articles
- URL: https://journals.rcsi.science/0869-2106/article/view/38477
- DOI: https://doi.org/10.18821/0869-2106-2018-24-2-104-108
- ID: 38477
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Abstract
The article considers clinical manifestations, pathogenesis and therapy of complex regional pain syndrome. The historical reference on this issue is provided. The description of clinical case of complex regional pain syndrome with positive effect against the background of applied therapy is presented. It is emphasized that besides complications related to monitoring of this category of patients, the presented case is an evidence of inadequate studying of pathogenesis of complex regional pain syndrome. The pathophysiologic concepts explaining development of complex regional pain syndrome are presented: activation of neurogenous inflammatory alterations, development of pathologic sympathetic afferent links and neuroplastic alterations in central nervous system. The focus is made on mal-adaptive character of neuroplastic alterations of sensory and motor cortex. The results of modern neuro-visual methods of study are analyzed permitting to look from a new perspective on origin of clinical disorders in this condition. The significance of disorders of cerebral links in case of complex regional pain syndrome. These results are based on analysis of functional links («connectom in rest»), temporarily and space characteristics of which are altered in presence of chronic pain. The conclusion is made that the very impact of functional links altered under complex regional pain syndrome provides possibilities for new methods of treatment of this state.
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##article.viewOnOriginalSite##About the authors
Igor V. Damulin
The I.M. Sechenov first Moscow state medical university of the Ministry of Health of the Russian Federation; The Moscow clinical scientific practical center of the Moscow Health Department
Email: damulin@mmascience.ru
doctor of medical sciences, professor of the chair of nervous diseases and neurosurgery The I.M. Sechenov first Moscow state medical university, 119991, Moscow 119991, Moscow, Russian Federation; 111123, Moscow, Russian Federation
A. A Galaeva
The I.M. Sechenov first Moscow state medical university of the Ministry of Health of the Russian Federation119991, Moscow, Russian Federation
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