HELICOBACTER PILORI AND BRONCHIAL ASTHMA IN CHILDREN


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Abstract

The results of clinical laboratory, endoscopic and morphologic analyses in children with bronchial asthma and concurrent chronic gastritis demonstrated that the level of total IgE has no significant differences in groups of patients with different degree of Helicobacter contamination and with the absence of Helicobacter pilori. At that, in 78% of patients the IgE level significantly exceeded the normal values. In case of absence of Helicobacter pilori, the lymfo-follicular hyperplasia of mucous membrane of the stomach was detected only in 12% of patients and in presence of Helicobacter pilori in 58.3% of patients. This case is probably related to the intensity of local immune response to Helicobacter infection. In the group of children with bronchial asthma and Helicobacter pilori high contamination the exacerbation of chronic gastritis proceeded in a more severe form.

About the authors

V. Kh Sosura

The I.M. Sechenov first Moscow state medical university

д-р мед. наук, проф.

A. Ya Shershevskaya

The I.M. Sechenov first Moscow state medical university

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