Estimate of Nonuniformity of Dose Distribution in Regime of Total Therapeutic Irradiation with In Vivo Dosimetry Using Semiconductor Detectors
- Authors: Lebedenko I.M.1,2, Khromov S.S.1, Neudakhin D.V.1, Belova A.A.1
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Affiliations:
- Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
- National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
- Issue: Vol 61, No 8 (2018)
- Pages: 836-839
- Section: Medical and Biological Measurements
- URL: https://journals.rcsi.science/0543-1972/article/view/246575
- DOI: https://doi.org/10.1007/s11018-018-1511-5
- ID: 246575
Cite item
Abstract
We have estimated the nonuniformity of the dose distribution along the body of a patient using in vivo dosimetry by semiconductor detectors with total therapeutic irradiation of cancer patients before bone marrow transplantation. The method of in vivo dosimetry was developed and used at the Blokhin Oncology Center since 2007. Based on the results of the investigation of 35 patients, we determined a mean nonuniformity of 10–15% of the dose distribution along the body of the patient, which conforms to international recommendations. We show a linear dependence of the accumulated dose on the mass of the patient.
About the authors
I. M. Lebedenko
Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation; National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
Author for correspondence.
Email: imlebedenko@mail.ru
Russian Federation, Moscow; Moscow
S. S. Khromov
Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
Email: imlebedenko@mail.ru
Russian Federation, Moscow
D. V. Neudakhin
Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
Email: imlebedenko@mail.ru
Russian Federation, Moscow
A. A. Belova
Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
Email: imlebedenko@mail.ru
Russian Federation, Moscow