| Dublin Core |
PKP Metadata Items |
Metadata for this Document |
| 1. |
Title |
Title of document |
Synthesis of 4,6-disubstituted bicyclo[3.3.1]nona-3,6-dien-2-ones |
| 2. |
Creator |
Author's name, affiliation, country |
S. G Mikhalyonok; Belarusian State Technological University |
| 2. |
Creator |
Author's name, affiliation, country |
V. S Bezborodov; Belarusian State Technological University |
| 2. |
Creator |
Author's name, affiliation, country |
N. M Kuz'menok; Belarusian State Technological University |
| 2. |
Creator |
Author's name, affiliation, country |
A. I Savelyev; Belarusian State Technological University |
| 2. |
Creator |
Author's name, affiliation, country |
A. S Arol; Belarusian State Technological University |
| 3. |
Subject |
Discipline(s) |
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| 3. |
Subject |
Keyword(s) |
Mannich base; cyclohex-2-enone; Michael addition; aldol condensation; bicyclo[3.3.1]nona-3,6-dien-2-one |
| 4. |
Description |
Abstract |
Bicyclo[3.3.1]nonane system is an important structural motif observed in a diverse natural products. Here, we report a concise synthetic route exploiting aldol condensation reactions for construction bicyclo[3.3.1]nonane ring system. Our strategy employes cyclohex-2-enones bearing another carbonyl group in side chain as key structural unit. The reaction showed good results for substrates bearing electron-donating groups in aromatic substituents. Overall, the described synthesis of bicyclo[3.3.1]nona-3,6-dien-2-ones required 2 steps and only 2 building blocks (such as Mannich base and acetoacetic ester) to access desired bicyclic system. |
| 5. |
Publisher |
Organizing agency, location |
The Russian Academy of Sciences |
| 6. |
Contributor |
Sponsor(s) |
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| 7. |
Date |
(DD-MM-YYYY) |
15.07.2023
|
| 8. |
Type |
Status & genre |
Peer-reviewed Article |
| 8. |
Type |
Type |
Research Article |
| 9. |
Format |
File format |
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| 10. |
Identifier |
Uniform Resource Identifier |
https://journals.rcsi.science/0514-7492/article/view/141661 |
| 10. |
Identifier |
Digital Object Identifier (DOI) |
10.31857/S0514749223070078 |
| 10. |
Identifier |
eLIBRARY Document Number (EDN) |
HTAMSF |
| 11. |
Source |
Title; vol., no. (year) |
Russian Journal of Organic Chemistry; Vol 59, No 7 (2023) |
| 12. |
Language |
English=en |
ru |
| 13. |
Relation |
Supp. Files |
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| 14. |
Coverage |
Geo-spatial location, chronological period, research sample (gender, age, etc.) |
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| 15. |
Rights |
Copyright and permissions |
Copyright (c) 2023 Russian Academy of Sciences
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