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Synthesis of Conjugates of Maleopimaric Acid with Nonsteroidal Anti-inflammatory drugs
- Authors: Vafina G.F.1, Poptsov A.I.1
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Affiliations:
- Ufa Institute of Chemistry, Ufa Federal Research Centre, of the Russian Academy of Sciences (UFRC RAS)
- Issue: Vol 61, No 11 (2025)
- Pages: 1550–1556
- Section: ЭКСПЕРИМЕНТАЛЬНЫЕ СТАТЬИ
- URL: https://journals.rcsi.science/0514-7492/article/view/381750
- DOI: https://doi.org/10.7868/S3034630425110026
- ID: 381750
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Abstract
New conjugates were synthesized by the reaction of acetylsalicylic acid chlorides, naproxen, ibuprofen and ketoprofen with amine-containing derivatives at the 2- and 6-positions of maleopimaric acid. The structure of the synthesized compounds was proven by NMR and mass spectroscopy methods, and elemental analysis data.
About the authors
G. F. Vafina
Ufa Institute of Chemistry, Ufa Federal Research Centre, of the Russian Academy of Sciences (UFRC RAS)
Author for correspondence.
Email: vafina@anrb.ru
ORCID iD: 0000-0002-9985-7711
Ufa, Russia
A. I. Poptsov
Ufa Institute of Chemistry, Ufa Federal Research Centre, of the Russian Academy of Sciences (UFRC RAS)
Email: vafina@anrb.ru
ORCID iD: 0000-0002-5193-7931
Ufa, Russia
References
- Silvestre A.J.D., Gandini A. Monomers, Polymers and Composites from Renewable Resources. Rosin: Major sources, properties and applications. Amsterdam, The Netherlands: Elsevier, 2008, 4, 67–88.
- Maiti S., Ray S.S., Kundu A.K. Prog. Polym. Sci. 1989, 297–338. https://doi.org/10.1016/0079-6700(89)90005-1
- Ding C., Matharu A.S. ACS Sustain. Chem. Eng. 2014, 2, 2217–2236. https://doi.org/10.1021/sc500478f
- Yao G., Ye M., Huang R., Li Y., Zhu Y., Pan Y., Liao Zh., Wang H. Bioorg. Med. Chem. Lett. 2013, 6755–6758. https://doi.org/10.1016/j.bmcl.2013.10.028
- Danswan G.W., Ramm P.J., Taylor J.B. Arzneimittel-Forschung. 1976, 2188–2189. PMID: 1037271.
- Wang J., Chen Y.P., Yao K., Wilbon P.A., Zhang W., Ren L., Zhou J., Nagarkatti M., Wang Ch., Chu F., He X., Decho A.W., Tang Ch. Chem. Comm. 2012, 916–918. https://doi.org/10.1039/c1cc16432e
- Sultanova R.M., Lobov A.N., Shumadalova A.V., Meshcheryakova S.A., Zileeva Z.R., Khusnutdinova N.S., Vakhitov V.A., Vakhitova Y.V. Nat. Prod. Res. 2019, 1340–1348. https://doi.org/10.1080/14786419.2019.1648459
- Вафина Г.Ф., Ханова М.Д., Мещерякова С.А., Булгаков А.К. ХПС. 2019, 55, 746–748. Vafina G.F., Khanova M.D., Meshcheryakova S.A., Bulgakov A.K. Chem. Nat. Compd. 2019, 55, 868–870. https://doi.org/10.1007/s10600-019-02835-z
- Толстиков Г.А., Толстикова Т.Г., Шульц Э.Э., Толстиков С.Е., Хвостов М.В. Смоляные кислоты хвойных России. Химия, фармакология. Новосибирск: Гео, 2011. 395 с.
- Kugler S., Ossowicz P., Malarczyk-Matusiak K., Wierzbicka E. Molecules. 2019, 1651. https://doi.org/10.3390/molecules24091651
- Lin G.-S., Dong S.-Q., Duan W.-G., Cen B., Xu X.-T., Yang, Z.-Q. Holzforschung. 2013, 68, 549–554. https://doi.org/10.1515/hf-2013-0124
- Вафина Г.Ф., Ханова М.Д., Есаулкова Я.Л., Синегубова Е.О., Слита А.В., Зарубаев В.В. ХПС. 2021, 57 (2), 276–279 Vafina G.F., Khanova M.D., Esaulkova Ya. L., Sinegubova E.O., Slita A.V., Zarubaev V.V. Chem. Nat. Compd., 2021, 57 (2), 323–326. https://doi.org/10.1007/s10600-021-03341-х
- Чулаков Е.Н., Груздев Д.А., Левит Г.Л., Садретдинова Л.Ш., Краснов В.П., Чарушин В.Н. Изв. АН, Сер. хим. 2011, 60 (5), 926–931. Chulakov E.N., Gruzdev D.A., Levit G.L., Sadretdinova L.Sh., Krasnov V.P., Charushin V.N. Russ. Chem. Bull. 2011, 60, 948–954. https://doi.org/10.1007/s11172-011-0149-0
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