Synthesis of 4-(4-Azidobenzyl)Phenol and N-[4-(4-Azidobenzyl)Phenyl]Acetamide

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Abstract

By diazotizing the aromatic amines N-[4-(4-aminobenzyl)phenyl]acetamide and 4-(4-aminobenzyl) phenol in the presence of excess hydrochloric acid with sodium nitrite and subsequent interaction of the diazonium salts obtained as a result of the reaction with sodium azide at a temperature from 0 to –5°C, N-[4-(4-azidobenzyl)phenyl]acetamide and 4-(4-azidobenzyl)phenol were obtained in yields of 57 and 55%.

About the authors

A. N. Teregulova

Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences

Email: kinetic@anrb.ru
ORCID iD: 0000-0003-4033-1261
prosp. Oktyabrya, 71, Ufa, 450054 Russia

A. N. Lobov

Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences

Email: kinetic@anrb.ru
ORCID iD: 0000-0002-9223-508X
prosp. Oktyabrya, 71, Ufa, 450054 Russia

R. L. Safiullin

Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences

Email: kinetic@anrb.ru
ORCID iD: 0000-0003-4830-1681
prosp. Oktyabrya, 71, Ufa, 450054 Russia

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