Regio- and Stereoselective Synthesis of New (Z)-Selenocyanatoacrylamides

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Abstract

A regio- and stereoselective synthesis of new vinyl selenocyanates (yields 76–93 %), containing N-alkylamide groups and heterocyclic amide substituents, has been developed based on the reaction of 3-trimethylsilyl-2-propynamides with potassium selenocyanate. The reaction proceeds in the presence of ammonium chloride in aqueous acetonitrile and is accompanied by a desilylation process.

About the authors

M. V. Andreev

A.E. Favorsky Irkutsk Institute of Chemistry, Federal Research Center, Siberian Branch of the Russian Academy of Sciences

ORCID iD: 0000-0002-0147-799X
Irkutsk, Russia

V. A. Potapov

A.E. Favorsky Irkutsk Institute of Chemistry, Federal Research Center, Siberian Branch of the Russian Academy of Sciences

Email: v.a.potapov@mail.ru
ORCID iD: 0000-0002-3151-6726
Irkutsk, Russia

M. V. Musalov

A.E. Favorsky Irkutsk Institute of Chemistry, Federal Research Center, Siberian Branch of the Russian Academy of Sciences

ORCID iD: 0000-0002-7638-8377
Irkutsk, Russia

L. I. Larina

A.E. Favorsky Irkutsk Institute of Chemistry, Federal Research Center, Siberian Branch of the Russian Academy of Sciences

ORCID iD: 0000-0002-7388-712X
Irkutsk, Russia

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