Synthesis of New 9-Selenabicyclo[4.2.1]Nonane Derivatives Based on the Transannular Addition Reaction of Selenium Dihalides to 1,3-Cyclooctadiene

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Abstract

The transannular addition reaction of selenium dichloride and dibromide to 1,3- cyclooctadiene was carried out for the first time. Based on this reaction, regio- and stereoselective approaches to new 2,3- bifunctional derivatives of 9- selenabicyclo[4.2.1]nonane with endo- exo and endo- endo stereochemistry have been developed. Conditions for stereoselective transannular anti, syn- and anti, anti- addition reactions have been found. A method for the sequential introduction of two different functional groups into the 9- selenabicyclo[4.2.1]nonane structure has been developed.

About the authors

M. V. Musalov

A.E. Favorsky Irkutsk Institute of Chemistry, Federal Research Center, Siberian Branch of the Russian Academy of Sciences

ORCID iD: 0000-0002-7638-8377
Irkutsk, Russia

A. A. Pakeeva

A.E. Favorsky Irkutsk Institute of Chemistry, Federal Research Center, Siberian Branch of the Russian Academy of Sciences

Irkutsk, Russia

V. A. Potapov

A.E. Favorsky Irkutsk Institute of Chemistry, Federal Research Center, Siberian Branch of the Russian Academy of Sciences

Email: v.a.potapov@mail.ru
ORCID iD: 0000-0002-3151-6726
Irkutsk, Russia

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