Cyclization of ethyl [cyano(4,6-dimethylpyrimidin-2-yl)amino]-acetate

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Abstract

Imidazolin-4-one derivatives have been prepared by a reaction of ethyl [cyano(4,6-dimethylpyrimidin-2-yl)amino]acetate (2) with morpholine, piperidine and hydrazides. In the presence of sulfuric acid, cyanoester 2 gives 2-iminooxazolin-5-one which is acylated on the nitrogen atom of imino group and is rearranged to imidzolidin-2,4-dione in the presence of KCNO.

About the authors

A. K. Shiryaev

Samara State Technical University

Email: shiryaev.ak@samgtu.ru
Russia, 443100 Samara, ul. Molodogvardeiskaya, 244

M. S. Krasavina

Samara State Technical University

Russia, 443100 Samara, ul. Molodogvardeiskaya, 244

V. A. Shiryaev

Samara State Technical University

Russia, 443100 Samara, ul. Molodogvardeiskaya, 244

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