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Synthesis of (S)-N-ethyl-2-(5-methylene-4-oxocyclopent-2-en-1-yl)acetamide – a model exomethylidenecyclopentenone bioisoster of prostamides
- Authors: Gimazetdinov A.M.1, Makaev Z.R.1, Miftakhov M.S.1
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Affiliations:
- Ufa Institute of Chemistry UFRS RAS
- Issue: Vol 61, No 3 (2025)
- Pages: 246-252
- Section: ЭКСПЕРИМЕНТАЛЬНЫЕ СТАТЬИ
- URL: https://journals.rcsi.science/0514-7492/article/view/304572
- DOI: https://doi.org/10.31857/S0514749225030049
- EDN: https://elibrary.ru/ettotn
- ID: 304572
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Abstract
The synthesis of the exo-methylidenecyclopentenone amide given in the title of the article from the methyl ester 2-{(1R,2R,5R)-2-[((tert-butyl(dimethyl)silyloxymethyl]-5-(trimethylsilyl)cyclopent-3-en-1-yl}acetic acid.
About the authors
A. M. Gimazetdinov
Ufa Institute of Chemistry UFRS RAS
Email: gimazetdinov@anrb.ru
prosp. Oktyabrya, 71, Ufa, 450054 Russia
Z. R. Makaev
Ufa Institute of Chemistry UFRS RASprosp. Oktyabrya, 71, Ufa, 450054 Russia
M. S. Miftakhov
Ufa Institute of Chemistry UFRS RASprosp. Oktyabrya, 71, Ufa, 450054 Russia
References
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