Oxidative Monofluorination of 1,4-Diiodo(or Dibromo)-2,3,5,6-tetramethylbenzenes in the System PbO₂—HF—Py—CH₂Cl₂

M. V. Kalyaev; Каляев М. В.; D. S. Ryabukhin; Рябухин Дмитрий Сергеевич; A. V. Vasilyev; Васильев Александр Викторович

doi:10.31857/S0514749224020011

Oxidative Monofluorination of 1,4-Diiodo(or Dibromo)-2,3,5,6-tetramethylbenzenes in the System PbO₂—HF—Py—CH₂Cl₂

作者: Kalyaev M.V.¹^,2, Ryabukhin D.S.¹^,3, Vasilyev A.V.¹^,2
隶属关系:
1. Saint Petersburg State Forest Technical University
2. Saint Petersburg State University
3. All-Russia Research Institute for Food Additives, V.M. Gorbatov Federal Research Center for Food Systems of RAS
期: 卷 60, 编号 2-3 (2024)
页面: 146–150
栏目: Articles
URL: https://journals.rcsi.science/0514-7492/article/view/274699
DOI: https://doi.org/10.31857/S0514749224020011
EDN: https://elibrary.ru/EKKJSS
ID: 274699

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详细

The oxidation of 1,4-diiodo-2,3,5,6-tetramethylbenzene (diiododurene) and 1,4-dibromo-2,3,5,6-tetramethylbenzene (dibromodurene) by lead dioxide PbO₂ in Olah reagent, hydrogen fluoride-pyridine mixture, with CH₂Cl₂as a co-solventat room temperature for 96 h results in the corresponding products of monofluorination of methyl group. This is the first example of using the oxidative system PbO₂—HF—Py—CH₂Cl₂ for side-chain monofluorination of methylated benzenes.

关键词

oxidation, lead dioxide, hydrogen fluoride-pyridine, monofluorination, radicalcations

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作者简介

M. Kalyaev

Saint Petersburg State Forest Technical University; Saint Petersburg State University

Email: aleksvasil@mail.ru
俄罗斯联邦, Institutsky per., 5, Saint Petersburg, 194021; Universitetskaya nab., 7/9, Saint Petersburg, 199034

D. Ryabukhin

Saint Petersburg State Forest Technical University; All-Russia Research Institute for Food Additives, V.M. Gorbatov Federal Research Center for Food Systems of RAS

Email: aleksvasil@mail.ru
ORCID iD: 0000-0001-5345-0038
俄罗斯联邦, Institutsky per., 5, Saint Petersburg, 194021; Liteyniy pr., 55, Saint Petersburg, 191014

A. Vasilyev

Saint Petersburg State Forest Technical University; Saint Petersburg State University

编辑信件的主要联系方式.
Email: aleksvasil@mail.ru
ORCID iD: 0000-0003-3628-1492
俄罗斯联邦, Institutsky per., 5, Saint Petersburg, 194021; Universitetskaya nab., 7/9, Saint Petersburg, 199034

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