Viruses and bats: interdisciplinary issues

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The virologists’ attention to bats (Сhiroptera) changed in the late 20th century as the concept of emerging infections grew in popularity. Since the beginning of the COVID-19 pandemic, the number of publications on bat viruses has increased profoundly.

History of the problem; biodiversity of Chiroptera and related viruses; medical and veterinary significance of some viral genera and subgenera (Lyssavirus, Henipavirus, Marburgvirus, Ebolavirus, Sarbecovirus, Merbecovirus), as well as problems of bat protection, are addressed in a concise form. Literature search was carried out in electronic databases, mainly for the period of 2000–2021. Publications in Russian that are poorly represented in English-language reviews are also included. The purpose of the review is to substantiate the importance of an interdisciplinary approach in the context of increased interest in the study of viral infections in bats. This review was written for researchers who have not previously dealt with this problem.

Since the beginning of this century, the number of known virus species associated with bats has increased by an order of magnitude (>200). The families Rhabdoviridae, Coronaviridae, Paramyxoviridae are in the first ranks according to the number of findings, and the highest diversity of viruses has been established for the families Vespertilionidae, Pteropodidae, Molossidae. Interdisciplinary cooperation positively influences the efficiency, biological safety and practical significance of the ongoing research. The best results were achieved by multidisciplinary teams with good cross-training in several specialties. Many papers emphasize the need to balance health and conservation interests.

The analysis of scientific publications indicates a change in research approaches in this area: from collecting individual facts within the framework of narrow specialties to a comprehensive assessment of new knowledge from ecological, evolutionary and socio-economic positions. Results of the research emphasize the need to maintain complex approaches addressing public health needs and environmental protection. The importance of bat-borne viral infections determines the necessity for correction and interdepartmental coordination of scientific research and surveillance of wildlife zoonoses in the Russian Federation.

作者简介

A. Botvinkin

FSBEI HE «Irkutsk State Medical University» of the Ministry of Health of Russia

编辑信件的主要联系方式.
Email: botvinkin_ismu@mail.ru
ORCID iD: 0000-0002-1324-7374

Aleksandr D. Botvinkin, D.Sci. (Med.), Head of Epidemiology Department.

664003, Irkutsk, Russia

俄罗斯联邦

参考

  1. Baer G.M., ed. The Natural History of Rabies. New York, San Francisco, London: Academic press; 1975.
  2. Павловский Е.Н. Основы учения о природной очаговости трансмиссивных болезней человека. Журнал общей биологии. 1946; (7): 3–33.
  3. Newman S.H., Field H.E., de Long С.E., Epstein J.N., eds. Food and Agriculture Organization of the United Nations. Investigating the Role of Bats in Emerging Zoonozes. Balancing Ecology, Conservation and Public Health Interest. Manual No 12. Rome: FAO Animal Production and Health; 2011.
  4. Леншин С.В., Ромашин А.В., Вышемирский О.И., Львов Д.К., Альховский С.В. Летучие мыши субтропической зоны Краснодарского края как возможный резервуар зоонозных вирусных инфекций. Вопросы вирусологии. 2021; 66(2): 112–22. https://doi.org/10.36233/0507-4088-41
  5. Calisher C.H., Childs J.E., Field H.E., Holmes K.V., Schountz T. Bats: important reservoir hosts of emerging viruses. Clin. Microbiol. Rev. 2006; 19(3): 531–45. https://doi.org/10.1128/CMR.00017-06
  6. Lederberg J., Shope R.E., Oaks S.C., eds. Emerging Infections: Microbial Threats to Health in the United States. Washington: National Academies Press; 1992.
  7. Moratelli R., Calisher C.H. Bats and zoonotic viruses: can we confidently link bats with emerging deadly viruses? Mem. Inst. Oswaldo Cruz. 2015; 110(1): 1–22. https://doi.org/10.1590/0074-02760150048
  8. Wang L.-F., Cowled C., eds. Bats and Viruses: A New Frontier of Emerging Infectious Diseases. Hoboken, New Jersey: John Wiley & Sons, Inc.; 2015. https://doi.org/10.1002/9781118818824
  9. Макаров В.В., Лозовой Д.А. Новые особо опасные инфекции, ассоциированные с рукокрылыми. Владимир; 2016.
  10. Corrales-Aguilar E., Schwemmle M., eds. Bats and Viruses: Current Research and Future Trends. Caister: Academic Press; 2020.
  11. Поршаков А.М., Кононова Ю.В., Локтев В.Б., Boiro M.I. Рукокрылые как возможный резервуар опасных для человека вирусов на территории Гвинейской Республики. Часть 1. Проблемы особо опасных инфекций. 2018; (3): 32–9. https://doi.org/10.21055/0370-1069-2018-3-32-39
  12. Поршаков А.М., Кононова Ю.В., Локтев В.Б., Boiro M.I. Рукокрылые как возможный резервуар опасных для человека вирусов на территории Гвинейской Республики. Часть 2. Проблемы особо опасных инфекций. 2018; (4): 20–6. https://doi.org/10.21055/0370-1069-2018-4-20-26
  13. Макаров В.В., Барсуков О.Ю. Эмерджентные зоонозы, ассоциированные с рукокрылыми. Пест-менеджмент. 2019; (2): 18–2. https://doi.org/10.25732/PM.2019.110.2.003
  14. Поршаков А.М., Кононова Ю.В., Лыонг Т.М. Филовирусы Юго-Восточной Азии, Китая и Европы (обзор литературы). Журнал инфектологии. 2019; 11(2): 5–13. https://doi.org/10.22625/2072-6732-2019-11-2-5-13
  15. Сизикова Т.Е., Боярская Н.В., Ковальчук А.В., Лебедев В.Н., Борисевич С.В. Новые представители семейства Filoviridae: распространение, природные резервуары, потенциальная эпидемическая опасность. Вестник войск РХБ защиты. 2019; 3(4): 329–36. https://doi.org/10.35825/2587-5728-2019-3-4-329-336
  16. Львов Д.К., Альховский С.В. Истоки пандемии COVID-19: эко- логия и генетика коронавирусов (Betacoronavirus: Coronaviridae) SARS-CoV, SARS-CoV-2 (подрод Sarbecovirus), MERS-CoV (подрод Merbecovirus). Вопросы вирусологии. 2020; 65(2): 62–70. https://doi.org/10.36233/0507-4088-2020-65-2-62-70
  17. Шестопалов А.М., Кононова Ю.В., Гаджиев А.А., Гуляева М.А., Маранди М.В., Алексеев А.Ю., и др. Биоразнообразие и эпидемический потенциал коронавирусов (Nidovirales: Coronaviridae) рукокрылых. Юг России: экология, развитие. 2020; 15(2): 17–34. https://doi.org/10.18470/1992-1098-2020-2-17-34
  18. Должикова И.В., Щербинин Д.Н., Логунов Д.Ю., Гинцбург А.Л. Вирус Эбола (Filoviridae: Ebolavirus: Zaire ebolavirus): фатальные адаптационные мутации. Вопросы вирусологии. 2021; 66(1): 7–16. https://doi.org/10.36233/0507-4088-23
  19. Puechmaille S.J., Ar Gouilh M., Dechmann D., Fenton B., Geiselman C., Medellin R., et al. Misconceptions and misinformation about bats and viruses. Int. J. Infect. Dis. 2021; 105: 606–7. https://doi.org/10.1016/j.ijid.2021.02.097
  20. Егоров А.Ю., Романова Ю.Р. Влияние глобального распределения летучих мышей на смертность у пациентов с COVID-19. Microbiol. Indep. Res. J. 2020; 7(1): 34–41. https://doi.org/10.18527/2500-2236-2020-7-1-34-41
  21. Chen L., Liu B., Yang J., Jin Q. DBatVir: the database of bat-associated viruses. Database. 2014; 2014: bau021. https://doi.org/10.1093/database/bau021
  22. Щелканов М.Ю., Дунаева М.Н., Москвина Т.В., Воронова А.Н., Кононова Ю.В., Воробьёва В.В., и др. Каталог вирусов рукокрылых (2020). Юг России: экология, развитие. 2020; 15(3): 6–30. https://doi.org/10.18470/1992-1098-2020-3-6-30
  23. Hermida Lorenzo R.J., Cadar D., Koundouno F.R., Juste J., Bialonski A., Baum H., et al. Metagenomic snapshots of viral components in Guinean bats. Microorganisms. 2021; 9(3): 599. https://doi.org/10.3390/microorganisms9030599
  24. International Committee on Taxonomy of Viruses. Available at: https://talk.ictvonline.org (accessed 24 July 2021).
  25. Wilson D.E., Mittermeier R.A. Handbook of the Mammalians of the World. Volume 9: Bats. Barcelona: Lynx Ediciones. 2019. Available at: https://www.lynxeds.com/product/handbook-of-the-mammalsof-the-world-volume-9/ (accessed 24 July 2021).
  26. Тиунов М.П., Крускоп С.В., Орлова М.В. Рукокрылые Дальнего Востока России и их эктопаразиты. М.: Перо; 2021.
  27. Российская рабочая группа по рукокрылым. Available at: https://zmmu.msu.ru/bats/rbgrhp/rbrg.htm (accessed 20 July 2021).
  28. IUCN: International Union for Conservation of Nature. Available at: https://www.iucn.org (accessed 24 July 2021).
  29. Luis A.D., Hayman D.T.S., O’Shea T.J., Cryan P.M., Gilbert A.T., Pulliam J.R.C., et al. A comparison of bats and rodents as reservoirs of zoonotic viruses: are bats special? Proc. Biol. Sci. 2013; 280: 20122753. https://doi.org/10.1098/rspb.2012.2753
  30. Gorbunova V., Seluanov A., Kennedy B.K. The world goes bats: living longer and tolerating viruses. Cell Metabolism. 2020; 32(1): 31–43. https://doi.org/10.1016/j.cmet.2020.06.013
  31. Rupprecht C., Kuzmin I., Meslin F. Lyssaviruses and rabies: current conundrums, concerns, contradictions and controversies. F1000Research. 2017; 6: 184. https://doi.org/10.12688/f1000research.10416.1
  32. Epstein J.H., Anthony S.J., Islam A., Kilpatrick A.M., Ali Khan S., Balkey M.D., et al. Nipah virus dynamics in bats and implications for spillover to humans. Proc. Natl. Acad. Sci. USA. 2020; 117(46): 29190–201. https://doi.org/10.1073/pnas.2000429117
  33. WHO. Coronavirus (COVID-19) Dashboard. Available at: https://covid19.who.int (accessed 17 July 2021).
  34. Banyard A.C., Evans J.S., Luo T.R., Fooks A.R. Lyssaviruses and bats: emergence and zoonotic threat. Viruses. 2014; 6(8): 2974–90. https://doi.org/10.3390/v6082974
  35. Ботвинкин А.Д. Смертельные случаи заболевания людей бешенством в Евразии после контактов с рукокрылыми (обзор литературы). Plecotus et al. 2011; (14): 75–86. Available at: https://zmmu.msu.ru/bats/biblio/rabies.pdf (accessed 17 July 2021).
  36. Kuzmin I.V., Botvinkin A.D., Poleschuk E.M., Orciari L.A., Rupprecht C.E. Bat rabies surveillance in the former Soviet Union. Dev. Biol. (Basel). 2006; 125: 273–82.
  37. Терновой В.А., Зайковская А.В., Томиленко А.А., Аксёнов В.И., Чаусов Е.В., Шестопалов А.М. Лиссавирусы у летучих мышей, обитающих на юге Западной Сибири. Вопросы вирусологии. 2005; 50(1): 31–4.
  38. Lu Z.L., Wang W., Yin W.L., Tang H.B., Pan Y., Liang X., et al. Lyssavirus surveillance in bats of southern China’s Guangxi Province. Virus Genes. 2013; (2): 293–301. https://doi.org/10.1007/s11262-012-0854-2
  39. Drexler J.F., Corman V.M., Muller M.A., Maganga G.D., Vallo P., Binger T., et al. Bats host major mammalian paramyxoviruses. Nat. Commun. 2012; 3: 796. https://doi.org/10.1038/ncomms1796
  40. Sharma V., Kaushik S., Kumar R., Yadav J.P., Kaushik S. Emerging trends of Nipah virus: A review. Rev. Med. Virol. 2019; (1): e2010. https://doi.org/10.1002/rmv.2010
  41. Williamson K.M., Wheeler S., Kerr J., Bennett J., Freeman P., Kohlhagen J., et al., BatOneHealth field team. Hendra in the Hunter Valley. One Health. 2020; 10: 100162. https://doi.org/10.1016/j.onehlt.2020.100162
  42. Kuzmin I.V., Niezgoda M., Franka R., Agwanda B., Markotter W., Breiman R.F., et al. Marburg virus in fruit bat, Kenya. Emerg. Infect. Dis. 2010; 16(2): 352–4. https://doi.org/10.3201/eid1602.091269
  43. Koch L.K., Cunze S., Kochmann J., Klimpel S. Bats as putative Zaire ebolavirus reservoir hosts and their habitat suitability in Africa. Sci. Rep. 2020; 10(1): 14268. https://doi.org/10.1038/s41598-020-71226-0
  44. Negredo A., Palacios G., Vázquez-Morón S., González F., Dopazo H., Molero F., et al. Discovery of an ebolavirus-like filovirus in Europe. PLoS Pathog. 2011; 7(10): e1002304. https://doi.org/10.1371/journal.ppat.1002304
  45. Li W., Shi Z., Yu M., Ren W., Smith C., Epstein J.H., et al. Bats are natural reservoirs of SARS-like coronaviruses. Science. 2005; 310(5748): 676–9. https://doi.org/10.1126/science.1118391
  46. Luk H.K.H., Li X., Fung J., Lau S.K.P., Woo P.C.Y. Molecular epidemiology, evolution and phylogeny of SARS coronavirus. Infect. Genet. Evol. 2019; 71: 21–30. https://doi.org/10.1016/j.meegid.2019.03.001
  47. Leitner T., Kumar S. Where did SARS-CoV-2 come from? Mol. Biol. Evol. 2020; 37(9): 2463–4. https://doi.org/10.1093/molbev/msaa162
  48. Ji W., Wang W., Zhao X., Zai J., Li X. Cross-species transmission of the newly identified coronavirus 2019-nCoV. J. Med. Virol. 2020; 92(4): 433–40. https://doi.org/10.1002/jmv.25682
  49. Olival K.J., Cryan P.M., Amman B.R., Baric R.S., Blehert D.S., Brook C.E., et al. Possibility for reverse zoonotic transmission of SARSCoV-2 to free-ranging wildlife: A case study of bats. PLoS Pathog. 2020; 16(9): e1008758. https://doi.org/10.1371/journal.ppat.1008758
  50. Wolfe N.D., Dunavan C.P., Diamond J. Origins of major human infectious diseases. Nature. 2007; 447(7142): 279–83. https://doi.org/10.1038/nature05775
  51. Patyk K., Turmelle A., Blanton J.D., Rupprecht C.E. Trends in national surveillance data for bat rabies in the United States: 2001–2009. Vector. Borne. Zoonotic. Dis. 2012; 12(8): 666–73. https://doi.org/10.1089/vbz.2011.0839
  52. Schatz J., Fooks A.R., McElhinney L., Horton D., Echevarria J., Vázquez-Moron S., et al. Bat rabies surveillance in Europe. Zoonoses Public Health. 2013; 60(1): 22–34. https://doi.org/10.1111/zph.12002
  53. Phelps K.L., Hamel L., Alhmoud N., Ali S., Bilgin R., Sidamonidze K., et al. Bat research networks and viral surveillance: gaps and opportunities in Western Asia. Viruses. 2019; 11(3): 240. https://doi.org/10.3390/v11030240
  54. Транквилевский Д.В., Жуков В.И., Царенко В.А. Вероятность заражения населения возбудителями, ассоциированными с рукокрылыми, в Российской Федерации. Здоровье населения и среда обитания. 2018; (3): 32–7. https://doi.org/10.35627/2219-5238/2018-300-3-32-37
  55. Voigt C.C., Kingston T., eds. Bats in the Anthropocene: conservation of bats in a changing world. Cham: Springer; 2016. https://doi.org/10.1007/978-3-319-25220-9_1
  56. Bat Concervation International. Available at: https://www.batcon.org (accessed 24 July 2021).
  57. UNEP/EUROBATS. Agreement on the сonservation of populations of European bats. Available at: https://www.eurobats.org/ (accessed 24 July 2021).
  58. Melber M., Gloza-Rausch F., Voigt C.C. Statement on handling of bats in times of Covid-19 regarding the IUCN Bat Specialists Groups recommendations of field activities for the protection of bats. Available at: https://bvfledermaus.de/wp-content/uploads/2020/04/BVF_Statement_on_Handling_of_Bats_in_times_of_Covid_19.pdf (accessed 24 July 2021).
  59. Германчук В.Г., Семакова А.П., Шавина Н.Ю. Этические принципы при обращении с лабораторными животными в эксперименте с патогенными биологическими агентами I–II групп. Проблемы особо опасных инфекций. 2018; (4): 33–8. https://doi.org/10.21055/0370-1069-2018-4-33-38
  60. Cunningham A.A., Daszak P., Wood J.L.N. One Health, emerging infectious diseases and wildlife: two decades of progress? Philos. Trans. R. Soc. Lond. B. Biol. Sci. 2017; 372(1725): 20160167. https://doi.org/10.1098/rstb.2016.0167

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