Email this article Peculiarities of the biological action of intense laser pulses at the molecular level
- Authors: Bugay A.N.1
-
Affiliations:
- Joint Institute for Nuclear Research
- Issue: Vol 88, No 6 (2024)
- Pages: 884-888
- Section: Quantum Optics and Coherent Spectroscopy
- URL: https://journals.rcsi.science/0367-6765/article/view/276165
- DOI: https://doi.org/10.31857/S0367676524060061
- EDN: https://elibrary.ru/PHHLGE
- ID: 276165
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Abstract
A biophysical model has been proposed for the formation of the main types of radiation damage to DNA in mammalian and human cells under action of intense femtosecond pulses in the visible and near-IR ranges.
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About the authors
A. N. Bugay
Joint Institute for Nuclear Research
Author for correspondence.
Email: bugay@jinr.ru
Russian Federation, Dubna
References
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Fig. 1. Calculation of the number of basic types of DNA damage per filament in a cell as a function of the peak intensity of a pulse with a wavelength of 0.8 μm, duration of 100 fs, and transverse radius of 1 μm. Solid line - base damage, dashed line - single-strand breaks, dashed line - DNA double-strand breaks
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Fig. 2. Calculation of the number of DNA DRs per filament in a cell as a function of the peak intensity of a 100 fs pulse with a duration of 100 fs and a transverse radius of 1 μm at different wavelengths: 0.6 μm (solid line), 0.8 μm (dashed line), 1 μm (dashed line)
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