Characteristics of Cold Atmospheric Plasma Jet when Excited by Sinusoidal and Positive Pulse Voltages for Medical Applications

I. V. Schweigert; Швейгерт И. В.; D. E. Zakrevskyc; Закревский Д. Э.; E. V. Milakhina; Милахина Е. В.; P. P. Gugin; Гугин П. П.; M. M. Birykov; Бирюков М. М.; E. A. Patrakova; Патракова Е. А.; O. S. Troitskaya; Троицкая О. С.; O. A.  Koval; Коваль О. А.

doi:10.31857/S0367292122601400

Characteristics of Cold Atmospheric Plasma Jet when Excited by Sinusoidal and Positive Pulse Voltages for Medical Applications

Authors: Schweigert I.V.¹, Zakrevskyc D.E.²^,3^,1, Milakhina E.V.²^,1, Gugin P.P.³^,1, Birykov M.M.⁴^,5^,1, Patrakova E.A.⁴, Troitskaya O.S.⁴^,1, Koval O.A.⁶^,7
Affiliations:
1. Khristianovich Institute of Theoretical and Applied Mechanics, SB Russian Academy of Sciences
2. Novosibirsk State Technical University
3. Rzhanov Institute of Semiconductor Physics, SB Russian Academy of Sciences
4. Institute of Chemical Biology and Fundamental Medicine, SB Russian Academy of Sciences
5. Novosibirsk State University
6. Khristianovich Institute of Theoretical and Applied Mechanics, Siberian Branch, Russian Academy of Sciences
7. Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
Issue: Vol 49, No 5 (2023)
Pages: 447-453
Section: LOW TEMPERATURE PLASMA
URL: https://journals.rcsi.science/0367-2921/article/view/139601
DOI: https://doi.org/10.31857/S0367292122601400
EDN: https://elibrary.ru/VEFPZI
ID: 139601

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Abstract

Low-temperature plasma jets at atmospheric pressure generated by sinusoidal and positive pulsed voltages interact differently with the treated surface. In the experiment and in numerical simulations, we compare the operating modes of helium plasma jets for these types of operating voltages. The discharge current on the treated surface over time and the surface heating are studied for different discharge parameters acceptable for anticancer therapy. The intensity of the emission spectrum is analyzed to improve the effectiveness of the plasma jet. Surface heating is controlled in order to meet the safety conditions of plasma exposure to biological objects. For the case of pulsed voltage the effect of voltage pulse duration on the intensity of plasma-surface interaction is discussed. The results on cancer cells A549 and MCF-7 demonstrate the high efficiency of the cold plasma jet generated at found optimal modes.

Keywords

cold plasma jet, positive pulsed voltage, pulse length, surface temperature, optimization

References

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