A model of human cardiovascular system containing a loop for the autonomic control of mean blood pressure
- Авторы: Karavaev A.1,2, Ishbulatov Y.1, Kiselev A.1,3,4, Ponomarenko V.1,2, Prokhorov M.2, Mironov S.5, Shvartz V.4, Gridnev V.1,3, Bezruchko B.1,2
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Учреждения:
- Chernyshevsky Saratov State University
- Saratov Branch, Kotelnikov Institute of Radio Engineering and Electronics
- Razumovsky Saratov State Medical University
- Bakoulev Scientific Center for Cardiovascular Surgery
- Central Military Hospital
- Выпуск: Том 43, № 1 (2017)
- Страницы: 61-70
- Раздел: Article
- URL: https://journals.rcsi.science/0362-1197/article/view/177092
- DOI: https://doi.org/10.1134/S0362119716060098
- ID: 177092
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Аннотация
We propose a model for the human cardiovascular system that describes the cardiac cycle, the autonomic regulation of heart and vessels, the baroreflex, and the formation of blood pressure. The model also allows for the influence of respiration on these processes. It has been found that an allowance for nonlinearity and insertion of a loop for the autonomic control of mean blood pressure (having the form of selfoscillating time-delay system) enables obtaining model signals with statistical and spectral characteristics that are qualitatively and quantitatively similar to those for experimental signals. The model reproduces the phenomenon of synchronization of the loop for mean blood pressure regulation with a basic frequency of approximately 10 s by the signal of respiration.
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Об авторах
A. Karavaev
Chernyshevsky Saratov State University; Saratov Branch, Kotelnikov Institute of Radio Engineering and Electronics
Email: antonkis@list.ru
Россия, Saratov, 410012; Saratov, 410019
Yu. Ishbulatov
Chernyshevsky Saratov State University
Email: antonkis@list.ru
Россия, Saratov, 410012
A. Kiselev
Chernyshevsky Saratov State University; Razumovsky Saratov State Medical University; Bakoulev Scientific Center for Cardiovascular Surgery
Автор, ответственный за переписку.
Email: antonkis@list.ru
Россия, Saratov, 410012; Saratov, 410012; Moscow, 121552
V. Ponomarenko
Chernyshevsky Saratov State University; Saratov Branch, Kotelnikov Institute of Radio Engineering and Electronics
Email: antonkis@list.ru
Россия, Saratov, 410012; Saratov, 410019
M. Prokhorov
Saratov Branch, Kotelnikov Institute of Radio Engineering and Electronics
Email: antonkis@list.ru
Россия, Saratov, 410019
S. Mironov
Central Military Hospital
Email: antonkis@list.ru
Россия, Moscow, 123182
V. Shvartz
Bakoulev Scientific Center for Cardiovascular Surgery
Email: antonkis@list.ru
Россия, Moscow, 121552
V. Gridnev
Chernyshevsky Saratov State University; Razumovsky Saratov State Medical University
Email: antonkis@list.ru
Россия, Saratov, 410012; Saratov, 410012
B. Bezruchko
Chernyshevsky Saratov State University; Saratov Branch, Kotelnikov Institute of Radio Engineering and Electronics
Email: antonkis@list.ru
Россия, Saratov, 410012; Saratov, 410019